Objective： To observe the therapeutic efficacy of Fu＇s subcutaneous needling （FSN） with laser for postherpetic neuralgia and analyze its action mechanism. Methods： A total of 102 cases with postherpetic neuralgia were randomly allocated into a treatment group and a control group, 51 in each group. FSN with laser was used for patients in the treatment group, whereas electroacupuncture was used for patients in the control group. After 6 months of treatment, the total effective rates, action time and cure courses in recovery cases were compared between the two groups. Three months after the treatment was completed, a follow-up was done to compare relapse rates between the two groups. Results： The recovery and total effective rates in the treatment group were 56.9% and 94.1% respectively, versus 35.3% and 68.6% in the control group, showing statistical differences （P〈0.05）; the action time and cure courses in the observation group were significantly shorter than those in the control group （P〈0.05）; the relapse rate in the treatment group was 6.9%, versus 44.4% in the control group, showing a statistical difference （P〈0.05）. Conclusion： FSN with laser can obtain better effect for postherpetic neuralgia than electroacupuncture and pose lower relapse risks.