Professional training for mega-science projects is a matter of pressing concern. The National Research Nuclear University MEPhI (NRNU MEPhI) created online courses on the topic of Strategic Academic Units (SAU). These courses are published on the most popular international platforms for mass open educational resources: Coursera and edX. NRNU MEPhI online courses are also presented on the National Open Education Platform and the Educational Portal of NRNU MEPhI. NRNU MEPhI students participate in various modern international projects, including megaprojects of the Joint Institute for Nuclear Research (JINR) among which are creation of the NICA collider, experiments on the synthesis of new elements, research in the field of the physics of condensed state of matter and environmental science carried out at a high-resolution neutron source. At the initiative of the JINR University Centre, the JINR Educational Portal was created. It hosts online courses created by JINR scientists on the topic of mega-projects. The report discusses proposals on the possible integration of the efforts of NRNU MEPhI teachers and JINR scientists in creating a digital multidisciplinary educational environment, which will support formation of individual learning trajectories for professionals for their further work in mega-science projects.