A 36-year-old female of rural background presented in the outpatient services of psychiatry with the complaints of increased irritability, increased talkativeness, grandiose talks, increased physical activity, increased religiosity and reduced sleep for the past 1 month. 3 In our patient, there are many potential causes (tumor in the left temporal lobe, temporal lobectomy, brain tissue damage due to radiotherapy as well seizure episodes) that might have attributed to the development of psychiatric symptoms. Choosing valproate as a medication for seizure prophylaxis, will not only ensure a seizure-free recovery; its mood stabilizing property will also take care of manic symptoms as well as aggression.