Provider: - Institution: - Data provided by Europeana Collections- Rod Centaurea, porodica Asteracea, taksonomski je vrlo složen, a 80 od ukupno 400 do 700 vrsta nalazimo na području Republike Hrvatske. Cilj ovoga doktorskog rada bio je odrediti fitokemijski i citogenetski profil odabranih vrsta roda Centaurea: Centaurea ragusina, Centaurea rupestris i Centaurea solstitialis. Fitokemijski profil, određen kroz kemijski sastav izoliranih hlapljivih ulja, istražen je vezanim sustavom plinska kromatografija - masena spektrometrija. Citogenetski profil, određen kao veličina genoma i osnovni broj kromosoma istraživanih vrsta, istraživan je protočnom citometrijom i standardnim kariološkim metodama. Citogenetski profil fitokemijski proučavanih vrsta u skladu je s prethodnim istraživanjima, čime je utvrđena autentičnost istraživanih vrsta bez dvojbe prilikom botaničke determinacije. Dominantne su komponente hlapljivih ulja odabranih vrsta roda Centaurea neoksidirani i oksidirani seskviterpenski spojevi te neterpenske kiseline i ugljikovodici. Germakren D, -kariofilen i heksadekanska kiselina identificirani su u svim proučavanim eteričnim uljima. Izolirana hlapljiva ulja pokazuju slab antioksidacijski potencijal i slabu sposobnost inhibicije acetilkolinesteraze i butirilkolinesteraze kao i značajan antimikrobni potencijal.- The Centaurea genus, Asteraceae family, taxonomically is very complex. It contains 80 species from Croatia, of about 400 up to 700 in total. The aim of this doctoral thesis was to determine the phytochemical and cytogenetic profiles of selected Centaurea species: Centaurea ragusina, Centaurea rupestris and Centaurea solstitialis. Phytochemical profile, determined as chemical composition of isolated volatile oil, was assesed with associated gas chromatography-mass spectrometry. Cytogenetic profile, expressed as genome size and chromosome number, was assessed by flow cytometry and standard karyological methods. Cytogenetic profile of species selected for phytochemical research, is in accordance with previous research, which aproves authenticity of the studied taxa. Dominant components of volatile oils of Centaurea species are oxidized and nonoxidized sesquiterpenes, and nonterpene acids and hydrocarbons. Germacrene D, -caryophyllene and hexadecanoic acid are identified in all Centaurea volatile oils. Isolated volatile oil showed weak antioxidant potential and inhibiton of acetylcholinesterase and butyrylcholinesterase, as well as significant antimicrobial potential.- All metadata published by Europeana are available free of restriction under the Creative Commons CC0 1.0 Universal Public Domain Dedication. However, Europeana requests that you actively acknowledge and give attribution to all metadata sources including Europeana