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Consensus clinical scoring for suspected perioperative immediate hypersensitivity reactions [Elektronski vir]Hopkins, Philip M. ...Background: Grading schemes for severity of suspected allergic reactions have been applied to the perioperative setting, but there is no scoring system that estimates the likelihood that the reaction ... is an immediate hypersensitivity reaction. Such a score would be useful in evaluating current and proposed tests for the diagnosis of suspected perioperative immediate hypersensitivity reactions and culprit agents. Methods: We conducted a Delphi consensus process involving a panel of 25 international multidisciplinary experts in suspected perioperative allergy. Items were ranked according to appropriateness (on a scale of 1-9) and consensus, which informed development of a clinical scoring system. The scoring system was assessed by comparing scores generated for a series of clinical scenarios against ratings of panel members. Supplementary scores for mast cell tryptase were generated. Results: Two rounds of the Delphi process achieved stopping criteria for all statements. From an initial 60 statements, 43 were rated appropriate (median score 7 or more) and met agreement criteria (disagreement index <0.5); these were used in the clinical scoring system. The rating of clinical scenarios supported the validity of the scoring system. Although there was variability in the interpretation of changes in mast cell tryptase by the panel, we were able to include supplementary scores for mast cell tryptase. Conclusion: We used a robust consensus development process to devise a clinical scoring system for suspected perioperative immediate hypersensitivity reactions. This will enable objectivity and uniformity in the assessment of the sensitivity of diagnostic tests.Source: British journal of anaesthesia. - ISSN 1471-6771 (Vol. 123, iss. 1, Jul. 2019, str. e29-e37)Type of material - e-article ; adult, seriousPublish date - 2019Language - englishCOBISS.SI-ID - 2048509297
Author
Hopkins, Philip M. |
Cooke, Peter J. |
Clarke, Russel C. |
Guttormsen, Anne Berit, 1958- |
Platt, Peter R. |
Dewachter, Pascale |
Ebo, Didier G. |
Garcez, Tomaz |
Garvey, Lene Heise |
Hepner, David L. |
Kopač, Peter, 1979-
Topics
Allergy and immunology |
Anesthesia |
Anaphylaxis |
Drug hypersensitivity |
Drug-related side effects and adverse reactions |
Perioperative period |
Surgery |
Surgical procedures, operative |
Alergija in imunologija |
Anestezija |
Anafilaksija |
Preobčutljivost za zdravila |
Stranski in škodljivi učinki zdravil |
Perioperativno obdobje |
Kirurgija |
Operativni kirurški postopki
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Database name | Field | Year |
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Links to authors' personal bibliographies | Links to information on researchers in the SICRIS system |
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Hopkins, Philip M. | |
Cooke, Peter J. | |
Clarke, Russel C. | |
Guttormsen, Anne Berit, 1958- | |
Platt, Peter R. | |
Dewachter, Pascale | |
Ebo, Didier G. | |
Garcez, Tomaz | |
Garvey, Lene Heise | |
Hepner, David L. | |
Kopač, Peter, 1979- | 30983 |
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