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Assembly of a cohort of children treated for acute myeloid leukemia at free-standing children's hospitals in the United States using an administrative databaseKavčič, Marko, medicinaPediatric Health Information System data were used to establish a multi-centercohort of 1,686 children treated for newly diagnosed acute myeloidleukemia (AML). The cohort assembly process, which ... included myeloid leukemia ICD-9 discharge diagnosis codes and manual review of induction chemotherapy, was validated by chart review at a single institution. The use of ICD-9 codes alone resulted in a poor positive predictive value (PPV; 31%). Inclusion of the results from the chemotherapy review improved the PPV to 100%without compromising sensitivity (95.7%). This cohort provides a reliable source for future comparative effectiveness and clinical epidemiology studies in pediatric AML.Source: Pediatric blood & cancer. - ISSN 1545-5009 (Vol. 60, iss. 3, mar. 2013, str. 508-511)Type of material - article, component partPublish date - 2013Language - englishCOBISS.SI-ID - 669356
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Kavčič, Marko, medicina | 32049 |
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