Razvoj in validacija analizne metode za določanje bioloških označevalcev ftalatov in njihovih zamenjav v materinem mleku = Development and validation of the analytical method for determination of biomarkers of phthalates and their replacements in human breast milk : enoviti magistrski študij farmacije
Kosirnik, Neja
Ftalati se uporabljajo kot mehčala za plastiko in jih tako dandanes srečamo v številnih izdelkih. Pojavljajo se v kozmetiki, farmacevtskih oblogah, tekstilu, embalaži za hrano in tudi v živilih, ...kamor pridejo preko odpuščanja iz embalaže, ker niso kemijsko vezani na plastične polimere. V veliki meri smo jim izpostavljeni že od rojstva in imajo dokazane negativne učinke na zdravje, zato se je v preteklih letih povečalo raziskovanje izpostavljenosti in njihovih škodljivih učinkov. To se izvaja v obliki študij humanega biomonitoringa na različnih vzorcih, največkrat sta to urin ali kri. Vendar pa je pridobitev slednje preveč invazivna za najmlajšo populacijo; dojenčke. Ker so dojeni dojenčki ftalatom in drugim kemijskim motilcem endokrinega sistema lahko potencialno izpostavljeni preko njihovega glavnega vira hrane, materinega mleka, smo želeli ugotoviti, katerim metabolitom ftalatov in njihovim zamenjavam so izpostavljeni ter v kolikšni meri.
Type of material - master's thesis
; adult, serious
Publication and manufacture - Ljubljana : [N. Kosirnik], 2023
Knjižnica emšf 0000000542 KOSIRNIK NEJA Razvoj 0000001312 IN: 0017806
Knjižnica emšf 542 KOSIRNIK NEJA Razvoj 1312 IN: 0017806
available - reading room
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