Faculty of Pharmacy, Lj. (FFALJ)
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Mogu li pacijenti s arterijskom hipertenzijom i dijabetesom također imati dobrobit od primjene statina? = Do hypertensive and diabetic patients also benefit from statin therapy?Kos, Jernej, študent medicine ; Barbič-Žagar, Breda ; Grošelj, Mateja, farmacevtkaČimbenici rizika za kardiovaskularne bolesti (KVB) uključuju arterijsku hipertenziju, dijabetes i dislipidemiju. Moderne smjernice za prevenciju KVB preporučaju više mjera za smanjenje utjecaja ... navedenih čimbenika rizika, uključujući i farmakološko liječenje. Brojne kliničke studije su pokazale prednosti od snižavanja povišene razine kolesterola kod hipertenzivnih bolesnika. Pokazalo se da konkomitantna terapija za arterijsku hipertenziju i dislipidemiju značajno smanjuje rizik od KVB u usporedbi samo sa snižavanjem vrijednosti arterijskog tlaka i kolesterola u krvi. Kliničke studije s Krkinim atorvastatinom su također pokazale učinkovitost i sigurnost terapije smanjenja lipida kod hipertenzivnih bolesnika s dislipidemijom. Dobro je poznato da se rizik za aterosklerotsku kardiovaskularnu bolest kod bolesnika s dijabetesom povečava dva do četiri puta. Kliničke studije su pokazale da je terapija statinom takoŽer bila korisna i u bolesnika s dijabetesom. Subanalize studija s uključenim bolesnicima s dijabetesom koji su bili liječeni Krkinim atorvastatinom dokazale su prednosti i sigurnost takvog liječenja. Stoga, snižavanje visokih razina kolesterola u krvi kod bolesnika s hipertenzijom i dijabetesom donosi dodatne koristi bolesnicima.Source: Kardio list. - ISSN 1846-0836 (Vol. 6, no. 5-6, 2011, str. 80-84)Type of material - article, component partPublish date - 2011Language - croatian, englishCOBISS.SI-ID - 3426417
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Kos, Jernej, študent medicine | ![]() |
Barbič-Žagar, Breda | 22747 |
Grošelj, Mateja, farmacevtka | 30292 |
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