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MIB-1, AgNOR and DNA distribution parameters and their prognostic value in neuroendocrine tumours of the lungJütting, Uta ...One of the most important questions in clinical routine is to find out patients with good or worse prognosis to apply an optimal therapy scheme for each patient. In this study 58 patients with ... different neuroendocrine tumours of the lung were investigated. Histological sections were prepared with different stainings (MIB-1, AgNOR, Feulgen). By means of high resolution imagecytometry stereological parameters were derived which are indicators for proliferation, ploidy and kinetics of the tumours. Cox regression analysis wascalculated to test the significance of the parameters with regard to prognosis. The best parameter was MIB-1 which can easily be applied as a clinical standard staining and measurement.Source: Image analysis & stereology : official journal of the International Society for Stereology. - ISSN 1580-3139 (Vol. 19, no. 1, mar. 2000, str. 39-43)Type of material - article, component partPublish date - 2000Language - englishCOBISS.SI-ID - 11478233
Author
Jütting, Uta |
Gais, Peter |
Rodenacker, Karsten |
Böhm, Joachim |
Höfler, Heinz
Topics
Lung neoplasms |
Pathology |
Neuroendocrine tumors |
Pathology |
Prognosis |
Silver staining |
Neoplasm staging |
Survival analysis |
Dna |
Image processing, computer-assisted |
pljuča |
pljuične bolezni |
novotvorbe |
karcinom |
slikovna diagnostika |
prognoza
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source: Image analysis & stereology : official journal of the International Society for Stereology. - ISSN 1580-3139 (Vol. 19, no. 1, mar. 2000, str. 39-43)
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