Medical Library - Medical Teaching Hospital, Maribor (SBMB)
-
Pomen serumskega cistatina C za ugotavljanje okvare ledvic med kemoterapijoVrhovec, LevinMany cytotoxic agents used in antitumor therapies can cause a kidney damage. Therefore there is a necessity for regular kidney function monitoring before and during chemotherapy. Clearance tests have ... been proven to be the most accurate indicators for clinical assessment of glomerular filtration (CFR). Because of inconvenience of exogene markers (inulin, 51Cr-EDTA), endogenous creatinine clearance (ECC) is used in everyday routine work. Results obtained from ECC analysis can often be misleading due to inaccurate urine collectin. In order to avoid the inconvenient urine collecting, we are trying to find an easier and faster way of kidney function assessment. Cystatin C is a serum protein, which is a member of the cysteine proteinase inhibitors. It is produced by all nucleal cells and its production rate is independent of sex, nutrition status, acute and chronic diseases and cancer. Because it is freely filtered at the glomerulus, its serum concentration correlates with glomerular filtration rate. The purpose of this research was to find out if the serum cystatine C concentration correlates with GFR and ECC respectively. We analysed 117 serum samples taken from 56 patients. Serum and urine creatinine concentrations were determined by method based on Jaffe reaction, ECC: was calculated from urine flow, surface area and the ratio between serum and urine creatinine concentrations. We used particle enhanced turbidimetric immunoassay (PET) for cystatin C determination. Data were statistically analysed with SimStat computer program. We used Pearson correlation method with 95% confidence interval. A good correlation coefficient (r =0.736) between the values of serum creatinine and cystatine C was established within the whole concentration interval. (Abstract truncated at 2000 characters.)Source: Medicinski razgledi : [medicinski pregledni, strokovni in raziskovalni članki]. - ISSN 0025-8121 (Letn. 39, št. 1, mar. 2000, str. 33-50)Type of material - article, component partPublish date - 2000Language - slovenianCOBISS.SI-ID - 11474137
source: Medicinski razgledi : [medicinski pregledni, strokovni in raziskovalni članki]. - ISSN 0025-8121 (Letn. 39, št. 1, mar. 2000, str. 33-50)
Shelf entry
Permalink
- URL:
Impact factor
Access to the JCR database is permitted only to users from Slovenia. Your current IP address is not on the list of IP addresses with access permission, and authentication with the relevant AAI accout is required.
Year | Impact factor | Edition | Category | Classification | ||||
---|---|---|---|---|---|---|---|---|
JCR | SNIP | JCR | SNIP | JCR | SNIP | JCR | SNIP |
Select the library membership card:
If the library membership card is not in the list,
add a new one.
DRS, in which the journal is indexed
Database name | Field | Year |
---|
Links to authors' personal bibliographies | Links to information on researchers in the SICRIS system |
---|---|
Vrhovec, Levin | 33049 |
Source: Personal bibliographies
and: SICRIS
Select pickup location:
Material pickup by post
Delivery address:
Address is missing from the member's data.
The address retrieval service is currently unavailable, please try again.
By clicking the "OK" button, you will confirm the pickup location selected above and complete the reservation process.
By clicking the "OK" button, you will confirm the above pickup location and delivery address, and complete the reservation process.
By clicking the "OK" button, you will confirm the address selected above and complete the reservation process.
Notification
Automatic login and reservation service currently not available. You can reserve the material on the Biblos portal or try again here later.
Subject headings in COBISS General List of Subject Headings
Select pickup location
The material from the parent unit is free. If the material is delivered to the pickup location from another unit, the library may charge you for this service.
Pickup location | Material status | Reservation |
---|
Reservation in progress
Please wait a moment.
Reservation was successful.
Reservation failed.
Reservation...
Membership card:
Pickup location: