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Avtoimunski hepatitis = Autoimmune hepatitisOcepek, Andreja ; Genslitskaya, EkaterinaAvtoimunski hepatitis je idiopatski hepatitis, pri katerem avtoimunske reakcije povzročajo kronični, redkeje akutni, vnetni proces v jetrnem tkivu. Bolezen se najpogosteje pojavi pri mladih ženskah. ... Pri avtoimunskem hepatitisu najdemo različna avtoprotitelesa proti sestavinam jetrnega tkiva. V diagnostiki avtoimunskega hepatitisa je pomembna izključitev drugih kroničnih jetrnih bolezni, v prid bolezni pa govorijo pretežni dvig transaminaz, hipergamaglobulinemija, prisotnost avtoprotiteles, spremljajoče druge avtoimunske bolezni, značilna histološka slika, pozitivni HLA DR3 ali DR4 in učinkovitost imunosupresivnega zdravljenja. V primeru ustreznega imunosupresivnega zdravljenja je potek bolezni dokaj ugoden, brez zdravljenja pa lahko napreduje do jetrne ciroze ali fulminantne jetrne odpovedi. Presaditev jeter je uspešna oblika zdravljenja izbranih bolnikov z 10-letnim preživetjem okrog 75 %.Source: [Zbornik predavanj in praktikum] (Str. 175-183)Type of material - conference contribution ; adult, seriousPublish date - 2011Language - slovenianCOBISS.SI-ID - 3950655
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Database name | Field | Year |
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Links to authors' personal bibliographies | Links to information on researchers in the SICRIS system |
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Ocepek, Andreja | 23927 |
Genslitskaya, Ekaterina |
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