Abstract Labral tears are the most common pathology in patients undergoing hip arthroscopy and the most common cause of mechanical hip symptoms. Labral repair techniques have been described in the ...literature using suture anchors placed as close as possible to the acetabular rim without penetrating the articular surface. Optimal surgical technique for labral repair is very important, and an inappropriate entry point and guide angulation may lead to intra-articular penetration of the anchor, chondral damage, anchor loosening, or inadequate fixation. A shallow dysplastic hip, the drilling trajectory, the narrow width of the acetabular rim, or some specific anatomic variations may generate difficulty during anchor placement. Suture anchors themselves have been associated with several significant complications, including rim fracture, osteolysis, enlargement of drill holes, and infection. The treatment of labral lesions with transosseous suture is an alternative to anchor use, eliminating the need for anchors and avoiding anchor-associated complications. This technique offers versatility to surgeons and is more cost-effective for patients and health services. We aim to describe the indications and technique for transosseous labral repair without anchors.
The aim of the present work was to investigate the anti-inflammatory and analgesic effects of red seaweed Dichotomaria obtusata, using classic tests in mice (ear edema induced by TPA and writhing ...induced by acetic acid). The qualitative chemical composition of the aqueous extract (lactones, phenols, triterpenes, steroids and reduced carbohydrates) obtained from this alga was also determined. The results showed that Dichotomaria obtusata (12.5, 25 and 50 mg/kg, ip) inhibited mouse ear edema in a dose-dependent manner. In the writhing test, aqueous extract (12.5, 25, 50 and 100 mg/kg, ip and 100, 200, 400, 800 mg/kg, po) significantly reduced abdominal writhes. In conclusion, this study demonstrated the anti-inflammatory and antinociceptive activities of aqueous extract of D. Obtusata in experimental models. These results suggest that D. obtusata aqueous extract possesses therapeutic potential in the treatment of peripheral painful or/and inflammatory conditions.
Marine red algae from central-southern coast of Cuba Moreira-González, Angel R.; Fernández-Garcés, Raúl; Gómez-Batista, Miguel ...
Regional studies in marine science,
January 2019, 2019-01-00, Volume:
25
Journal Article
Peer reviewed
The aim of this study was to carry out a taxonomic survey of red marine benthic algae that occur in the littoral zone of central-southern Cuba. The samplings were performed in the period 2010–2012at ...12 stations predominantly in reef environments. A total of 81 taxa were recorded and distributed in 9 orders and 24 families. Ceramiales was the most represented order with 38 taxa, followed by Corallinales with nine taxa. Hypoglossum caloglossoides represents a new record for Cuban benthic marine algae. Forty-nine species of macroalgae are new additions to the flora of reef environments from the central-southern region of Cuba. Sixty species of the region are provided in Figures (2–61). Dichotomaria obtusata was the most common species found. Some species such as Ceramium fujianum, Gloiocladia iyoensis, Griffithsia schousboei var. anastomosans and Dasya ocellata have been found in Cuba only in the central-southern region. Calcified crustose and articulated coralline algae were found to be common in the coral reef locations, while filamentous turfs and fleshy or frondose macroalgae were commonly found in the stations of shallow or intertidal waters. The floristic composition of red marine benthic algae indicates the central-southern coast of Cuban archipelago as a site of elevated species richness and that its coral reef environments are in a status of good health due to prevalence of calcareous coralline macroalgae.
•Marine benthic red algal diversity of central-southern coast of Cuba were studied.•A total of 81 taxa distributed in 9 orders and 24 families were documented.•Hypoglossum caloglossoides represents a new record for Cuban benthic marine algae.•Forty-nine species of macroalgae are new additions to the flora of reef environments from central-southern coast of Cuba.•The central-southern coast of Cuban archipelago shows a high species diversity.
The aim of the present work was to investigate the anti-inflammatory and antinociceptive effects of methanolic extract from D. obtusata using classic models in mice (croton oil-induced ear edema and ...acetic acid-induced writhing) and a phospholipase A2 activity test. Qualitative analysis of the chemical composition of seaweed was also determined by extraction with solvents of increasing polarity and precipitation and color tests. Results of qualitative chemical study showed the presence of lactonic and phenolic compounds, reduced carbohydrates, other sugars, flavonoids, fatty compounds, triterpenes and steroids. The extract inhibited mouse ear edema in a dose-dependent manner with an efficacy higher than 90% and a mean effective dose of 4.87µg/ear, while intraperitoneal administration presented a moderate activity. The extract did not inhibit phospholipase A2 activity. In the writhing test, the intraperitoneal administration of the extract showed a strong antinociceptive activity (80.2%), while the oral route showed a lower efficacy. In conclusion, this study demonstrated the anti-inflammatory and antinociceptive effects of methanol extract of D. obtusata in experimental models, suggesting its therapeutic potential in the treatment of peripheral painful and/or inflammatory pathologies.
O objetivo do presente trabalho foi investigar os efeitos antiinflamatórios e antinociceptivos de um extrato metanólico de D. obtusata, utilizando modelos clássicos em ratos (teste do edema de orelha induzido por óleo de cróton e teste de contorções induzidas por ácido acético) e um teste de atividade de fosfolipase A2. A análise qualitativa da composição química das algas foi também determinada através de extração com solventes de polaridade crescente e testes de precipitação e cor. Os resultados do estudo de química qualitativa mostraram a presença de compostos lactônicos e fenólicos, hidratos de carbono reduzidos e outros açúcares, flavonoides, compostos graxos, triterpenos e esteroides. O extrato inibiu o edema de orelha dos ratos de um modo dependente da dose com eficácia superior a 90% e dose média efetiva de 4.87µg/orelha, enquanto a administração intraperitoneal apresentou atividade moderada. O extrato não inibiu a atividade da fosfolipase A2. No teste de contorção, a administração intraperitoneal do extrato mostrou forte atividade antinociceptiva (80,2%), enquanto a administração oral mostrou menor eficácia. Em conclusão, este estudo demonstrou os efeitos antiinflamatórios e antinociceptivos do extrato metanólico de D. obtusata em modelos experimentais, sugerindo seu potencial terapêutico no tratamento de patologias dolorosas periféricas e/ou inflamatórias.
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