Clostridium difficile Infection in a Health Care Worker Hell, Markus; Indra, Alexander; Huhulescu, Steliana ...
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America,
05/2009, Volume:
48, Issue:
9
Report
Streptococcus zooepidemicus is a common animal pathogen. It infects domestic and laboratory animals and has been found to cause respiratory infections in horses and, infrequently, mastitis in cows. ...Clinical infections in humans are uncommon and are usually associated with ingestion of unpasteurized milk or contact with horses. In this article we present a fatal case of abdominal mycotic aneurysm in a 71-yr-old hotel owner who regularly consumed raw cow's milk.
Toxicity and clearance of intravitreal cefotetan Philipp, W; Schmid, K; Steiner, H J ...
Graefe's archive for clinical and experimental ophthalmology,
01/1990, Volume:
228, Issue:
5
Journal Article
Peer reviewed
Direct intravitreal injection of antibiotics plays an important role in the management of bacterial endophthalmitis. In the present study we investigated the toxicity and clearance of intravitreally ...injected cefotetan in a rabbit model. No toxic ocular side effects could be detected by electroretinography (ERG) or light and electron microscopy up to and including a single intravitreal dose of 1000 micrograms. Intravitreal injection of 2000 micrograms cefotetan resulted in mild degeneration of photoreceptor outer segments and, sporadically, in cataract formation. After intravitreal injection of 4000 micrograms, moderate toxic degeneration of photoreceptors occurred, with displacement and mitochondrial swelling of inner segments. In addition, lysosomal lamellar inclusion bodies could be detected in pigment epithelial cells. After a single intravitreal injection of 1000 micrograms cefotetan, concentrations greater than the minimum necessary for the inhibition of most commonly occurring intraocular pathogens (except Pseudomonas aeruginosa and Staphylococcus epidermidis) were maintained in the vitreous humor for greater than 48 h. Cefotetan may be a potentially important drug for intravitreal injection, especially in cases of gram-negative and suspected anaerobic endophthalmitis.
We used automated laser fluorescence analysis of randomly amplified polymorphic DNA (RAPD-Alfa) to study the epidemiology of listeriosis in western Austria. There were no discrepancies between ...RAPD-Alfa patterns and serotypes found in 18 food isolates and 18 clinical isolates. The results of our study suggest that the food isolates typed were not at the origin of the human cases in western Austria. Using RAPD-Alfa, it was possible to link 9 out of 16 “sporadic” Listeria infections (mother-child cases counted as one) to the occurrence of other cases. Our results underline the necessity of epidemiological clarification of listeriosis cases as a prerequisite for specific preventive measures by public health services (e. g. confiscation of contaminated food products, issue of public warnings). To establish the chain of infection, more is needed than just speciation of bacteria in incriminated food products. Automated laser fluorescence analysis of randomly amplified polymorphic DNA seems a suitable, easy and rapid method for the typing of
Listeria monocytogenes strains.
Microcalorimetric investigations on Listeria Allerberger, F J; Schulz, A; Dierich, M P
Zentralblatt für Bakteriologie, Mikrobiologie und Hygiene. Series A, Medical microbiology, infectious diseases, virology, parasitology,
03/1988, Volume:
268, Issue:
1
Journal Article
Sixty-one Listeria strains--Listeria monocytogenes (35 strains), Listeria ivanovii (8), Listeria innocua (7), Listeria welshimeri (6) and Listeria seeligeri (5)--were tested microcalorimetrically for ...their heat production upon growth in Columbia broth. Listeria ivanovii and Listeria seeligeri displayed different and quite characteristic thermograms. Listeria welshimeri, Listeria innocua and all but one of the Listeria monocytogenes strains showed similar microcalorimetric curves, which differed considerably from those of Listeria ivanovii and Listeria seeligeri.
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