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  • Species abundance distribut... Species abundance distributions: moving beyond single prediction theories to integration within an ecological framework
    McGill, Brian J; Etienne, Rampal S; Gray, John S ... Ecology letters, October 2007, Volume: 10, Issue: 10
    Journal Article
    Peer reviewed

    Species abundance distributions (SADs) follow one of ecology's oldest and most universal laws - every community shows a hollow curve or hyperbolic shape on a histogram with many rare species and just ...
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  • Tachykinin-Expressing Neuro... Tachykinin-Expressing Neurons Control Male-Specific Aggressive Arousal in Drosophila
    Asahina, Kenta; Watanabe, Kiichi; Duistermars, Brian J. ... Cell, 01/2014, Volume: 156, Issue: 1-2
    Journal Article
    Peer reviewed
    Open access

    Males of most species are more aggressive than females, but the neural mechanisms underlying this dimorphism are not clear. Here, we identify a neuron and a gene that control the higher level of ...
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  • Population dynamics of normal human blood inferred from somatic mutations
    Lee-Six, Henry; Øbro, Nina Friesgaard; Shepherd, Mairi S ... Nature (London), 09/2018, Volume: 561, Issue: 7724
    Journal Article
    Peer reviewed
    Open access

    Haematopoietic stem cells drive blood production, but their population size and lifetime dynamics have not been quantified directly in humans. Here we identified 129,582 spontaneous, genome-wide ...
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  • Paracetamol (Acetaminophen)... Paracetamol (Acetaminophen): mechanisms of action
    ANDERSON, BRIAN J. Pediatric anesthesia, October 2008, Volume: 18, Issue: 10
    Journal Article
    Peer reviewed
    Open access

    Summary Paracetamol has a central analgesic effect that is mediated through activation of descending serotonergic pathways. Debate exists about its primary site of action, which may be inhibition of ...
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  • Practicalities of Total Intravenous Anesthesia and Target-controlled Infusion in Children
    Anderson, Brian J; Bagshaw, Oliver Anesthesiology (Philadelphia), 07/2019, Volume: 131, Issue: 1
    Journal Article
    Peer reviewed

    Propofol administered in conjunction with an opioid such as remifentanil is used to provide total intravenous anesthesia for children. Drugs can be given as infusion controlled manually by the ...
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  • Allometric size: The scient... Allometric size: The scientific theory and extension to normal fat mass
    Holford, Nick H.G.; Anderson, Brian J. European journal of pharmaceutical sciences, 11/2017, Volume: 109
    Journal Article
    Peer reviewed

    1.There is a nonlinear relationship between structure and functional processes and the mass of living organisms. Allometric scaling of body mass provides a theory based method for predictions of mass ...
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  • Human neural stem cells dif... Human neural stem cells differentiate and promote locomotor recovery in an early chronic spinal cord injury NOD-scid mouse model
    Salazar, Desirée L; Uchida, Nobuko; Hamers, Frank P T ... PloS one, 08/2010, Volume: 5, Issue: 8
    Journal Article
    Peer reviewed
    Open access

    Traumatic spinal cord injury (SCI) results in partial or complete paralysis and is characterized by a loss of neurons and oligodendrocytes, axonal injury, and demyelination/dysmyelination of spared ...
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  • Mechanistic Basis of Using ... Mechanistic Basis of Using Body Size and Maturation to Predict Clearance in Humans
    Anderson, Brian J.; Holford, Nick H.G. DRUG METABOLISM AND PHARMACOKINETICS, 01/2009, Volume: 24, Issue: 1
    Journal Article
    Peer reviewed

    Growth and development are two major aspects of children not readily apparent in adults. Clearance in the paediatric population should be investigated using models that describe size, maturation and ...
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  • Interplanetary coronal mass... Interplanetary coronal mass ejections from MESSENGER orbital observations at Mercury
    Winslow, Reka M.; Lugaz, Noé; Philpott, Lydia C. ... Journal of geophysical research. Space physics, August 2015, Volume: 120, Issue: 8
    Journal Article
    Peer reviewed
    Open access

    We use observations from the MErcury Surface, Space ENvironment, GEochemistry, and Ranging (MESSENGER) spacecraft, in orbit around Mercury, to investigate interplanetary coronal mass ejections ...
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  • Pharmacokinetics and pharma... Pharmacokinetics and pharmacodynamics of dexmedetomidine‐induced vasoconstriction in healthy volunteers
    Talke, Pekka; Anderson, Brian J. British journal of clinical pharmacology, June 2018, Volume: 84, Issue: 6
    Journal Article
    Peer reviewed
    Open access

    Aims Alpha‐2 agonists are direct peripheral vasoconstrictors, which achieve these effects by activating vascular smooth muscle alpha‐2 adrenoceptors. The impact of this response during ...
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