Esta pesquisa objetivou identificar o que se publicou acerca do ensino de Probabilidade e Estatística no Encontro Baiano de Educação Matemática (EBEM), analisando e entendendo o que as publicações ...trazem à luz da Base Nacional Comum Curricular (BNCC) no que tange aos Anos Finais do Ensino Fundamental. Trata-se de um estudo de abordagem qualitativa desenvolvido a partir de uma pesquisa bibliográfica que teve como fonte os anais das edições de 2017, 2019 e 2021 desse evento. Após aplicados os critérios de inclusão e exclusão foram analisadas um quantitativo de 07 produções. Os resultados apontaram que poucas foram as produções publicadas no EBEM a respeito da unidade temática Probabilidade e Estatística voltadas para os Anos Finais do Ensino Fundamental, apesar de estar de todas as formas presentes em nosso cotidiano. Notamos ainda que a partir dos trabalhos selecionados, os autores buscavam analisar e ampliar a visão dos leitores acerca dos materiais tecnológicos, livros didáticos, jogos, ambientes de aprendizagem, cenários do dia a dia de alunos com a transdisciplinaridade e até mesmo a junção de disciplinas através da interdisciplinaridade. Concluímos ainda que ficou claro a importância de inovar as metodologias e os diferentes materiais que podem ser usados no ensino da Probabilidade e Estatística, positivando as estratégias formativas na aprendizagem dos estudantes.
Objetivo: Analisar os casos de hanseníase em menores de quinze anos. Métodos: Estudo de campo, quantitativo, transversal, série histórica e descritivo, com 48 casos de hanseníase entre 2009 a 2018 de ...Rondonópolis (MT). A coleta de dados utilizou prontuários do Serviço de Assistência Especializada e visitas domiciliárias. Foi utilizada estatística descritiva e testes Qui-quadrado e Exato de Fisher; nível de significância de 5%; foi calculada razão de chances e intervalos de confiança. Pesquisa aprovada pelo Comitê de Ética em Pesquisa (CAAE:97441618.2.0000.8088). Resultados: Os casos predominaram em 2013 (18,8%), sexo masculino (52%), faixa etária 10 a 14 anos (54,2%), multibacilar (64,6%) e tuberculóide (64,6%). Foi possível verificar associação estatística significativa entre classe operacional e renda familiar (p<0,0434) e ano de diagnóstico e classificação multibacilar (p<0,0189). Conclusões: O perfil dos casos e os fatores associados indicam alta transmissibilidade da doença e a dificuldade em realização do diagnóstico precoce no município em estudo.
Para celebrar os vinte anos da revista Interface, a equipe de Criação mergulhou no conjunto de materiais que foram publicados na seção de Criação desde o primeiro número da revista. O resultado é ...esta bricolagem de imagens, palavras e reflexões, que constituem recortes da multiplicidade de vozes que contam essa história. São tentativas de pensar a seção de Criação ontem e hoje, além de outros possíveis caminhos para a sua constante – e necessária – reinvenção. To celebrate the 20th anniversary of the journal Interface, members of the team responsible for the Creation section immersed themselves in a range of materials that have been published in the section since the journal’s very first issue. The result is an assortment of images, words and reflections that gives an insight as to the multiplicity of voices that tell this story. They represent attempts to think about the Creation section both nowadays and in the past, along with possible pathways for its on-going – and essential – reinvention. Para conmemorar los veinte años de la revista Interface el equipo de creación revisó profundamente el conjunto de materiales publicados en la sección de Creación desde el primer número de la revista. El resultado es este conjunto de imágenes, palabras y reflexiones que constituyen recortes de la multiplicidad de voces que cuentan esta historia. Son tentativas de pensar en la sección de Creación ayer y hoy, además de otros posibles caminos para su reinvención constante y necesaria.
This paper proposes the real-time estimation of the root-mean-square (rms) values, primary power quantities (active, total apparent, nonactive power, and power factor), and distortion power using the ...maximal overlap wavelet packet transform (MODWPT). The MODWPT provides a uniform frequency band and possesses the time-invariance property, which is ideal for the real-time power estimation. The performance of the proposed wavelet-based power measurement was assessed and compared to the IEEE Standard 1459-2010 in different case studies including stationary synthetic waveforms and power quality disturbances in experimental setup. The proposed method presented good results in the estimation of rms values and primary power quantities by using compact mother wavelets, whereas the estimation of distortion power was better with long mother wavelets.
http://dx.doi.org/10.5902/1980509820650Nativa da Bolívia e Argentina, Nicotiana glauca Graham, atualmente é encontrada crescendo espontaneamente em zonas áridas e semiáridas de diferentes partes do ...globo, sendo que, em alguns países, é considerada uma importante exótica invasora. No Brasil, a espécie ainda não havia sido reportada como invasora, mas nas áreas do Projeto de integração do Rio São Francisco (PISF), Nicotiana glauca pode ser observada formando aglomerados de indivíduos com altas densidades (mais de 37.000 indivíduos ha). Com isso, o objetivo do presente estudo foi inferir sobre a situação citada por meio de aspectos da estrutura (densidade, biometria e diversidade), reprodução (produção de frutos, propágulos e germinabilidade), presença de substâncias alelopáticas (extratos com concentrações de 0, 5, 10, 15 e 20%) e da susceptibilidade de ocorrência da espécie no Brasil. A densidade estimada para a espécie foi de 37.280±2.442,3 indivíduos ha. A planta pode produzir mais de 1.300.000 sementes por indivíduo. A partir da primeira concentração dos extratos (5%), a germinação das sementes, tamanho e biomassa de plântulas de Lactuca sativa foram afetados significativamente. A espécie apresentou alta probabilidade de ocorrência nas regiões de clima semiárido e subúmido do Brasil. Os resultados deste estudo demonstram a necessidade do controle imediato da espécie nas áreas do PISF e, subsidiam a formulação de meios para evitar novos casos de invasão biológica por Nicotiana glauca em outras partes do Brasil.
The recognition of ontogenetic edentulism in the Jurassic noasaurid Limusaurus inextricabilis shed new light on the dietary diversity within Ceratosauria, a stem lineage of non-avian theropod ...dinosaurs known for peculiar craniomandibular adaptations. Until now, edentulism in Ceratosauria was exclusive to adult individuals of Limusaurus. Here, an exceptionally complete skeleton of a new toothless ceratosaur, Berthasaura leopoldinae gen. et sp. nov., is described from the Cretaceous aeolian sandstones of the Bauru Basin, Southern Brazil. The specimen resembles adult individuals of Limusaurus by the absence of teeth but based on the unfused condition of several elements (e.g., skull, vertebral column) it clearly represents an ontogenetically immature individual, indicating that it might never have had teeth. The phylogenetic analysis performed here has nested Berthasaura leopoldinae as an early-divergent Noasauridae, not closely related to Limusaurus. It represents the most complete non-avian theropod from the Brazilian Cretaceous and preserves the most complete noasaurid axial series known so far. Moreover, the new taxon exhibits many novel osteological features, uncommon in non-avian theropods, and unprecedented even among South American ceratosaurs. These include not only toothless jaws but also a premaxilla with cutting occlusal edge, and a slightly downturned rostral tip. This indicate that B. leopoldinae unlikely had the same diet as other ceratosaurs, most being regarded as carnivorous. As the ontogenetically more mature specimens of Limusaurus, Berthasaura might have been herbivorous or at least omnivorous, corroborating with an early evolutionary divergence of noasaurids from the ceratosaurian bauplan by disparate feeding modes.
This article proposes a wavelet-based monitor (WBM) for grid impedance estimation, which combines a wavelet-based transient detection scheme (WB-TDS) and a wavelet-based grid impedance estimator ...(WB-GIE). The WB-TDS employs the analysis of the wavelet coefficients energy for detecting grid impedance changing, whereas the WB-GIE estimates the grid impedance by using the real-time stationary discrete wavelet packet transform associated with signal injection scheme. During a grid impedance changing, the WB-TDS triggers the WB-GIE for injecting an interharmonic into the power grid to estimate its current impedance. This method mitigates the total harmonic distortion generated by the continuous signal injection employed in the existing techniques. The WB-GIE identifies the phase grid impedance resistance and reactance accurately in balanced or unbalanced conditions. Due to its inherent characteristics, WBM is suitable to be inserted into the adaptive power flow control of distributed generation systems. Experimental results obtained from a grid-connected photovoltaic generation laboratory setup validates the proposed method and demonstrates its effectiveness.
Inflammatory bowel diseases (IBD) are characterized by a chronic and recurrent gastrointestinal condition, including mainly ulcerative colitis (UC) and Crohn's disease (CD).
(CS) is widely used for ...medicinal, recreational, and religious purposes. The most studied compound of CS is tetrahydrocannabinol (THC) and cannabidiol (CBD). Besides many relevant therapeutic roles such as anti-inflammatory and antioxidant properties, there is still much controversy about the consumption of this plant since the misuse can lead to serious health problems. Because of these reasons, the aim of this review is to investigate the effects of CS on the treatment of UC and CD. The literature search was performed in PubMed/Medline, PMC, EMBASE, and Cochrane databases. The use of CS leads to the improvement of UC and CD scores and quality of life. The medical use of CS is on the rise. Although the literature shows relevant antioxidant and anti-inflammatory effects that could improve UC and CD scores, it is still not possible to establish a treatment criterion since the studies have no standardization regarding the variety and part of the plant that is used, route of administration and doses. Therefore, we suggest caution in the use of CS in the therapeutic approach of IBD until clinical trials with standardization and a relevant number of patients are performed.
In the present study, acridine-thiosemicarbazones (ATD) derivatives were tested for their interaction properties with BSA through UV–Vis absorption and fluorescence spectroscopic studies. Both ...hyperchromic and hypochromic effects, as well as red or blue shifts were demonstrated after the derivatives were added to the BSA. Values for the binding constant (Kb) ranged from 1.62 × 104 to 8.71 × 105 M−1 and quenching constant (KSV) from 3.46 × 102 to 7.83 × 103 M−1 indicating a good affinity to BSA protein. Complementary, two compounds were selected to assess their inhibition activity against topoisomerase IIα enzyme, of which derivative 3a presented the best result. Moreover, to evaluate protein-ligand interactions, as well as the antitopoisomerase potential of these compounds, tests of molecular modeling were performed between all compounds using the albumin and Topoisomerase IIα/DNA complex. Finally, in silico studies showed that all derivatives used in this research displayed good oral bioavailability potential.
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•Acridine-thiosemicarbazone derivatives (ATD) bind to albumin.•Compound 3a (non-substituted phenyl) inhibited Topoisomerase IIα activity.•Molecular docking methods evidenced ATD binding to Topoisomerase IIα/DNA complex.
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