There is a scarcity of research on suicidal phenomena in the Muslim world. Therefore, this study aimed at investigating the self-reported prevalence of suicidal thoughts, attempts and motives in 12 ...Muslim countries. A total of 8417 (54.4% women) university students were surveyed by means of a self-report questionnaire. Overall, 22% of the participants reported suicidal ideation and 8.6% reported attempting suicide. The odds of suicidal thoughts were elevated in Azerbaijan, Indonesia and Saudi Arabia, while reduced ORs were recorded in Egypt, Jordan, Lebanon and Malaysia. While odds of suicide attempts were high in Azerbaijan, Palestine and Saudi Arabia reduced odds ratios (OR) were detected in Indonesia, Iran, Jordan, Lebanon, Malaysia and Tunisia. Taking drugs and using a sharp instrument were the two most frequently used methods to attempt suicide. Only 32.7% of attempts required medical attention. Escape motives were endorsed more than social motives by participants who attempted suicide. Suicidal behaviors were more frequent in women than in men. Compered to men, fewer attempts by women required medical attention. Moreover, our results show that making suicide illegal does not reduce the frequency of suicidal behavior. Results from this comparative study show that suicidal thoughts and attempts are frequent events in young adults in countries where religious scripture explicitly prohibit suicide and the frequencies of nonfatal suicidal behavior show large variation in nations adhering to the same religion.
Link of Video Abstract: https://youtu.be/TRnFAXBESHc
Background: Coronavirus disease 2019 (COVID-19) has become a significant disease causing a pandemic worldwide. Many variants were detected ...within the globe and may have an important role in transmission capability or reinfection conditions. The ‘unknown’ level of immunity’s protection from previous infection and the more virulent virus could lead to reinfection. Using the whole genome sequence, we can analyze the genomic insight within the first and second infections to help understand the reinfection pattern of COVID-19.
Methods: In this study, we investigated three COVID-19 cases with reinfection for primary and secondary infection each. The SARS-CoV-2 confirmation was conducted using qPCR with multiplex gene targets Orf1ab and E. Confirmation of reinfection was done by genomic analysis. Library preparation and sequencing were done using ARTIC protocol using nanopore technology.
Results: There was a wide variety of mutations between two episodes of infection and different clinical manifestations in each episode.
Conclusions: The result concluded that reinfection happened in worsened clinical symptoms and distinct genomic variation in each episode of infection
The study investigated the associations of religiosity, religious coping and suicide acceptance to suicide ideation and attempts in 7427 young adults affiliating with Islam from 11 Muslim countries.
...A self-administered questionnaire was used to collect the data. We used F and χ2 tests and correlation analyses to report descriptive statistics. Multi-group path models with (i) a zero-inflated Poisson distribution and, (ii) a Binomial distribution were used to model the number of occurrences of suicidal ideation, and occurrence of a suicide attempt, respectively.
Religiosity was negatively associated with acceptability of suicide, but it was positively related to punishment after death across the 11 countries. Religiosity was negatively associated with ever experiencing suicidal ideation, both directly and indirectly through its association with attitudes towards suicide, especially the belief in acceptability of suicide. Neither positive nor negative religious coping were related to suicidal ideation. However, religiosity was negatively related to suicide attempts among those who experienced suicidal ideation at least once. This association was mediated through the belief in acceptability of suicide and religious coping. Negative religious coping was positively associated with suicide attempts probably because it weakened the protective effects of religiosity.
Findings from this study suggest that the effects of religiosity in the suicidal process operate through attitudes towards suicide. We therefore conclude that clinical assessment as well as research in suicidology may benefit from paying due attention to attitudes towards suicide.
•Religiosity deters suicide through its effects on attitudes towards suicide.•Acceptability of suicide has the strongest links to suicidal thoughts and attempts.•Neither positive nor negative religious coping are related to suicidal ideation.•Negative religious coping is positively associated with suicide attempts.•Positive religious coping does not deter suicide attempts.
•Suicide acceptance and negative life-events were associated with suicidal ideation.•Perceived social support was negatively related to suicidal ideation.•Those who had interdependent self-construal ...were less accepting of suicide.•Number of life-events was the strongest predictor of ever attempting suicide.•Interdependence attenuated the association of negative life-events with suicide attempts.
Research on suicidality in low to middle-income countries is scarce. We addressed this issue by investigating suicidality in a cross-national college student samples from 11 predominantly low to middle-income majority Muslim countries.
The sample consisted of 7427 college students (56% female) who reported to be affiliated with Islam. Data on self-construal, social support, negative life-events, acceptability of suicide, suicidal ideation, and suicide attempts were collected with self-administered questionnaires.
Acceptability of suicide and the experience of negative life-events were positively, and perceived social support was negatively associated with suicidal ideation. Interdependent self-construal was negatively related to the acceptability of suicide and positively associated with perceived social support, implying a negative indirect effect on suicidal ideation although its direct effect was positive. The number of negative life-events was the strongest positive predictor of ever attempting suicide. The interdependent self-construal moderated the association of negative life-events with suicide attempts.
Cross-sectional and self-report nature of the study were its major limitations. Participants may have suppressed their responses about suicide because of religious and legal reasons.
Remarkable similarities across 11 country samples emerged in the linkages between cultural and interpersonal factors with suicidality. Our findings highlight the value of a nuanced approach to suicidality, that can recognize the differences in the processes associated with suicidal ideation and suicide attempts, as well as the need to consider the interplay of a broad range of personal, interpersonal, and cultural influences.
Small Mother Against Decapentaplegic 3 (SMAD3), an intracellular transducer protein in the TGF-β signaling pathway, has a role in maintaining joint cartilage. Many studies have been conducted to ...examine the effect of polymorphism in SMAD3 gene with the incidence of osteoarthritis (OA). The objective of this study is to identify the association of SMAD3 gene rs12901499 variation with the incidence of knee OA in Indonesian women. We conducted an analytic cross-sectional design involving 24 knee OA patients and 50 non-OA subjects. The DNA was taken from saliva and genotyped using a kit from Integrated DNA Technologies with the Real Time PCR method. In this study, we found that the GA genotype (heterozygous mutant) of the rs12901499 allele was the allele that most frequently (50%) appeared in knee OA patients as well as non-OA subjects (50%). The G allele frequency was higher than the A allele among all participants. The Chi-Square analysis showed that there was no statistically significant relationship between allele variations in the SMAD3 rs12901499 gene and knee OA (p=1). In conclusion, there was no statistically significant relationship between the rs12901499 genetic variation in the SMAD3 gene and the incidence of knee osteoarthritis in Indonesian aged women.
Background: Smoking is a form of risky behavior that often starts in adolescence and is continued into adulthood. There has also been an increase in the use of vaping among adolescents. Adolescents ...who smoke have a double the risk of having depression symptoms compared to those who don't smoke. Objectives: This study aimed to investigate smoking and vaping behaviors and the experience of depressive symptoms among high school students in Jakarta, Indonesia. Materials and Methods: This cross-sectional study used the Youth Risk Behavior Surveillance (YRBS) 2017 questionnaire. Participants included 258 students aged between 10 and 19, randomly chosen from three types of senior high schools in Jakarta. Results: We found that 21.5% of students frequently smoked in the last 30 days, and 8.1% vaped repeatedly. However, 70.5% of them tried vaping. Moreover, within the last 12 months, approximately 8.5% of the students attempted suicide at least once. Also, 32.9% of them felt sad and hopeless for two weeks. Interestingly, we found that 54.1% of the students who felt sad were frequent smokers, and 43.5% were regular vapers. Conclusions: This study showed that risky behaviors like smoking and vaping were prevalent among senior high school students in Jakarta. Students who smoked or vaped exhibited depressive symptoms. Therefore, smoking and vaping could affect mental health in adolescence.
•Accepting suicide was positively associated with escape motives for suicide.•Escape motives were negatively related to post-suicidal well-being.•Communication motives for suicide were not associated ...with post-suicidal well-being.•Interdependent self-construal might be beneficial for post-suicidal well-being.•Others’ interpretation of suicidal act may be critical for post-suicidal well-being.
This study focused on the well-being of the survivors of suicide attempts and the well-being of their interpersonal relationships after the attempt. The data came from a sample of 392 college students from 10 Muslim majority countries who reported having attempted suicide in the last 4 years. Suicide was conceptualized as a goal-directed behavior embedded in a sociocultural context and motivated by personal or interpersonal goals. We tested a process that linked culturally shaped self-construal to the postsuicidal personal and interpersonal well-being. We posited that this process would operate through the attitudes towards suicide, motives for suicide, the strength of the intention to die. Our model indicated that the acceptability of suicide was positively associated with escape motives, and this association was even stronger for the individuals with interdependent self-construals. Escape motives were negatively associated with postsuicidal personal and interpersonal well-being, but communication motives were not associated with these outcomes. We also found evidence that having an interdependent self-construal might be beneficial for postsuicidal personal and interpersonal well-being. Our results further suggested that the postsuicidal personal and interpersonal well-being of highly interdependent individuals may depend on the interpretation of their act of suicide by their close others.
Background: Physical exercises provide benefits for everyone. Riset Kesehatan Dasar 2018 shows increased proportion of Indonesian who lack of exercise from 26.1% to 33.5%. Inadequate exercise can ...reduce productivity which can lead to excessive internet use and increasing the severity of depression. Objectives: To know the association between duration of exercise against duration of internet usage and the severity of depression amongst Syarif Hidayatullah State Islamic University Jakarta students. Methods: This is a non-experimental quantitative cross-sectional study on students of State Islamic University Jakarta using Patient Health Questionnaire-9 instrument, which has been validated by Confirmatory Factor Analysis method. Data were analysed by (1) descriptive statistics to obtain respondents general characteristics and the variables, (2) independent sample T-test to analyze the mean difference between the variables of men and women, (3) linear regression test to examine the relationship between the variables. Results: From 704 respondents, we found that 62.1% lacked of exercise, 57.8% using internet excessively, and 71.3% suffering moderate to severe depression. Furthermore, these results were common in women. There was significant negative association between duration of exercise (p-value = 0.000) and duration of internet usage, significant negative association between duration of exercise (p-value = 0.000) with the severity of depression, and significant positive association between duration of internet usage (p-value = 0.031) with the severity of depression. Conclusions: There is a significant association between duration of exercise with duration of internet usage and the severity of depression amongst Syarif Hidayatullah State Islamic University Jakarta students. Keyword : Exercise, Excessive Internet Use, Internet Addiction, Depression, Patient Health Questionnaire-9 (PHQ-9)
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