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  • The potential use of the ne... The potential use of the neurotensin high affinity receptor 1 as a biomarker for cancer progression and as a component of personalized medicine in selective cancers
    Dupouy, Sandra; Mourra, Najat; Doan, Van Kien ... Biochimie, 09/2011, Volume: 93, Issue: 9
    Journal Article
    Peer reviewed

    A growing challenge in medicine today, is the need to improve the suitability of drug treatments for cancer patients. In this field, biomarkers have become the “flags” to provide additional ...
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  • Loss of glucocorticoid rece... Loss of glucocorticoid receptor activation is a hallmark of BRCA1-mutated breast tissue
    Vilasco, Myriam; Communal, Laudine; Hugon-Rodin, Justine ... Breast cancer research and treatment, 11/2013, Volume: 142, Issue: 2
    Journal Article
    Peer reviewed

    Glucocorticoids (GCs) regulate cell homeostasis and can affect carcinogenesis. An inherited germline mutation in the BRCA1 gene, a tumor suppressor gene, confers a predisposition to breast and ...
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  • Activation of EGFR, HER2 an... Activation of EGFR, HER2 and HER3 by neurotensin/neurotensin receptor 1 renders breast tumors aggressive yet highly responsive to lapatinib and metformin in mice
    Dupouy, Sandra; Doan, Van Kien; Wu, Zherui ... Oncotarget, 09/2014, Volume: 5, Issue: 18
    Journal Article
    Open access

    A present challenge in breast oncology research is to identify therapeutical targets which could impact tumor progression. Neurotensin (NTS) and its high affinity receptor (NTSR1) are up regulated in ...
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  • Clusterin Expression in Med... Clusterin Expression in Medullary Thyroid Carcinoma is Inversely Correlated with the Presence of Lymph Node Metastases
    Mourra, Najat, MD, PhD; Bennis, Malika, MD; Boelle, Pierre-Yves, MD, PhD ... Human pathology, 06/2017, Volume: 64
    Journal Article
    Peer reviewed

    Summary Clusterin (CLU) is a sulfated glycoprotein implicated in many physiological and pathological processes, including tumorigenesis. Several studies have reported the overexpression of CLU in ...
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  • Adrenalectomy for clinically isolated metastasis from colorectal carcinoma: report of eight cases
    Mourra, Najat; Hoeffel, Christine; Duvillard, Pierre ... Diseases of the colon & rectum, 2008-December, Volume: 51, Issue: 12
    Journal Article
    Peer reviewed

    Metastasis to the adrenal glands is a relatively frequent finding at autopsy. Adrenal metastasis of colorectal carcinoma is rare (14 percent). Isolated adrenal metastasis is even rarer, and presents ...
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  • Multicystic schwannoma of t... Multicystic schwannoma of the porta hepatis
    Mourra, Najat; Colignon, Nikias; Zaatari, Ghazi Clinics and research in hepatology and gastroenterology, September 2020, 2020-09-00, 20200901, Volume: 44, Issue: 4
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    Peer reviewed
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  • High frequency of chromosom... High frequency of chromosome 14 deletion in early-onset colon cancer
    Mourra, Najat; Zeitoun, Guy; Buecher, Bruno ... Diseases of the colon & rectum, 2007-November, Volume: 50, Issue: 11
    Journal Article
    Peer reviewed

    Several genes have been recognized, when mutated in the germline, to highly predispose to colorectal cancer, impairing the DNA mismatch repair system in hereditary nonpolyposis colon cancer syndrome, ...
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