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  • Histological and molecular ... Histological and molecular changes in gill and liver of fish (Astyanax lacustris Lütken, 1875) exposed to water from the Doce basin after the rupture of a mining tailings dam in Mariana, MG, Brazil
    Macêdo, Anderson Kelvin Saraiva; Santos, Keiza Priscila Enes dos; Brighenti, Ludmila Silva ... The Science of the total environment, 09/2020, Volume: 735
    Journal Article
    Peer reviewed

    The effects of the rupture of a mining tailings dam were investigated using the gills and liver of Astyanax lacustris as a proxy for environmental quality. The fish were exposed for seven days to ...
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  • Antioxidant, anti-inflammat... Antioxidant, anti-inflammatory, and wound healing effects of topical silver-doped zinc oxide and silver oxide nanocomposites
    Borges Rosa de Moura, Francyelle; Antonio Ferreira, Bruno; Helena Muniz, Elusca ... International journal of pharmaceutics, 04/2022, Volume: 617
    Journal Article
    Peer reviewed

    Display omitted Silver nanoparticles (Ag-NPs), silver oxide nanoparticles (AgO-NPs), and zinc oxide nanoparticles (ZnO-NPs) have healing, antibacterial, and antioxidant properties. Furthermore, ...
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  • Atrazine promotes immunomod... Atrazine promotes immunomodulation by melanomacrophage centre alterations in spleen and vascular disorders in gills from Oreochromis niloticus
    Oliveira, Sabrina Elisa; Costa, Pauliane Melo; Nascimento, Sara Batista ... Aquatic toxicology, 09/2018, Volume: 202
    Journal Article
    Peer reviewed

    •Atrazine causes an increase of aneurysm in gills of Nile tilapia.•Atrazine promotes an immunomodulation in different concentrations.•The melanomacrophage centres are responsive to atrazine ...
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  • Concomitant consumption of ... Concomitant consumption of marijuana, alcohol and tobacco in oral squamous cell carcinoma development and progression: Recent advances and challenges
    Lopes, Caio Fabio Baeta; de Angelis, Bruno Brandão; Prudente, Henrique Maciel ... Archives of oral biology, 08/2012, Volume: 57, Issue: 8
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    Peer reviewed

    Abstract Oral squamous cell carcinoma (OSCC) corresponds to 95% of all malignant tumours of the mouth. The association between alcohol and tobacco is the major risk factor for this disease, ...
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  • Proliferation, survival and... Proliferation, survival and cell death in fish gills remodeling: From injury to recovery
    Sales, Camila Ferreira; Santos, Keiza Priscila Enes dos; Rizzo, Elizete ... Fish & shellfish immunology, September 2017, 2017-Sep, 2017-09-00, 20170901, Volume: 68
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    Peer reviewed

    Pollutants found dispersed in water can cause irritations on the gills, challenge the immune system and prejudice the welfare of the fish. Here we investigated molecules linked to proliferation, ...
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  • WIN55,212-2 induces caspase... WIN55,212-2 induces caspase-independent apoptosis on human glioblastoma cells by regulating HSP70, p53 and Cathepsin D
    Silva, Ana Gabriela; Lopes, Caio Fabio Baeta; Carvalho Júnior, Clóvis Gomes ... Toxicology in vitro, June 2019, 2019-Jun, 2019-06-00, 20190601, Volume: 57
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    Despite the standard approaches to treat the highly aggressive and invasive glioblastoma (GBM), it remains incurable. In this sense, cannabinoids highlight as a promising tool, because this tumor ...
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  • Alkaloid and phenolic compo... Alkaloid and phenolic compounds of Xylopia aromatica inhibits tumor growth by down-regulating matrix metalloproteinase-2 (MMP-2) expression
    Gomes, Izabela Natalia Faria; Silva, Ana Gabriela; Frazao Lima, Gustavo Fernando de ... Pakistan journal of pharmaceutical sciences 34, Issue: 2
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    Peer reviewed

    Annonacea species have been reported to possess antitumor properties. However, the in vitro and in vivo antitumor activities of Xylopia aromatica (Annonacea) have not yet been elucidated. This study ...
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  • Sm16, A Schistosoma mansoni... Sm16, A Schistosoma mansoni Immunomodulatory Protein, Fails to Elicit a Protective Immune Response and Does Not Have an Essential Role in Parasite Survival in the Definitive Host
    Bernardes, Wilma Patrícia de Oliveira Santos; de Araújo, Juliano Michel; Carvalho, Gardênia Braz ... Journal of Immunology Research, 2019, Volume: 2019
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    Open access

    Sm16 is an immunomodulatory protein that seems to play a key role in the suppression of the cutaneous inflammatory response during Schistosoma mansoni penetration of the skin of definitive hosts. ...
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  • Reduced CD8+ T cells infilt... Reduced CD8+ T cells infiltration can be associated to a malignant transformation in potentially malignant oral epithelial lesions
    Chaves, Aline Lauda Freitas; Silva, Ana Gabriela; Maia, Flávia Medeiros ... Clinical oral investigations, 04/2019, Volume: 23, Issue: 4
    Journal Article
    Peer reviewed

    Objective The aim of this study was to evaluate the immunohistochemical expressions of PD1, CD4 + , and CD8 + in premalignant lesions (OPML) that were transformed into oral squamous cell carcinoma ...
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