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  • A novel framework for in-vi... A novel framework for in-vivo diffusion tensor distribution MRI of the human brain
    Magdoom, Kulam Najmudeen; Avram, Alexandru V.; Sarlls, Joelle E. ... NeuroImage (Orlando, Fla.), 05/2023, Volume: 271
    Journal Article
    Peer reviewed
    Open access

    •Developed a novel diffusion MRI framework for studying microscopic anisotropy and intra-voxel heterogeneity in tissue.•Implemented a multiple diffusion encoding method using interfused pulsed field ...
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  • Clinical feasibility of usi... Clinical feasibility of using mean apparent propagator (MAP) MRI to characterize brain tissue microstructure
    Avram, Alexandru V.; Sarlls, Joelle E.; Barnett, Alan S. ... NeuroImage (Orlando, Fla.), 02/2016, Volume: 127
    Journal Article
    Peer reviewed
    Open access

    Diffusion tensor imaging (DTI) is the most widely used method for characterizing noninvasively structural and architectural features of brain tissues. However, the assumption of a Gaussian spin ...
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  • Effects of image distortion... Effects of image distortions originating from susceptibility variations and concomitant fields on diffusion MRI tractography results
    Irfanoglu, M. Okan; Walker, Lindsay; Sarlls, Joelle ... NeuroImage (Orlando, Fla.), 05/2012, Volume: 61, Issue: 1
    Journal Article
    Peer reviewed
    Open access

    In this work we investigate the effects of echo planar imaging (EPI) distortions on diffusion tensor imaging (DTI) based fiber tractography results. We propose a simple experimental framework that ...
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  • Effectiveness of navigator-... Effectiveness of navigator-based prospective motion correction in MPRAGE data acquired at 3T
    Sarlls, Joelle E; Lalonde, Francois; Rettmann, Dan ... PloS one, 06/2018, Volume: 13, Issue: 6
    Journal Article
    Peer reviewed
    Open access

    In MRI, subject motion results in image artifacts. High-resolution 3D scans, like MPRAGE, are particularly susceptible to motion because of long scan times and acquisition of data over ...
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  • DR-BUDDI (Diffeomorphic Reg... DR-BUDDI (Diffeomorphic Registration for Blip-Up blip-Down Diffusion Imaging) method for correcting echo planar imaging distortions
    Irfanoglu, M. Okan; Modi, Pooja; Nayak, Amritha ... NeuroImage (Orlando, Fla.), 02/2015, Volume: 106
    Journal Article
    Peer reviewed
    Open access

    We propose an echo planar imaging (EPI) distortion correction method (DR-BUDDI), specialized for diffusion MRI, which uses data acquired twice with reversed phase encoding directions, often referred ...
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  • Whole-Brain Imaging of Subv... Whole-Brain Imaging of Subvoxel T1-Diffusion Correlation Spectra in Human Subjects
    Avram, Alexandru V.; Sarlls, Joelle E.; Basser, Peter J. Frontiers in neuroscience, 06/2021, Volume: 15
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    Open access

    T1 relaxation and water mobility generate eloquent MRI tissue contrasts with great diagnostic value in many neuroradiological applications. However, conventional methods do not adequately quantify ...
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  • Measuring non-parametric di... Measuring non-parametric distributions of intravoxel mean diffusivities using a clinical MRI scanner
    Avram, Alexandru V.; Sarlls, Joelle E.; Basser, Peter J. NeuroImage (Orlando, Fla.), 01/2019, Volume: 185
    Journal Article
    Peer reviewed
    Open access

    We measure spectra of water mobilities (i.e., mean diffusivities) from intravoxel pools in brain tissues of healthy subjects with a non-parametric approach. Using a single-shot isotropic diffusion ...
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  • Evaluating corrections for ... Evaluating corrections for Eddy‐currents and other EPI distortions in diffusion MRI: methodology and a dataset for benchmarking
    Irfanoglu, M. Okan; Sarlls, Joelle; Nayak, Amritha ... Magnetic resonance in medicine, April 2019, Volume: 81, Issue: 4
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    Peer reviewed
    Open access

    Purpose To propose a methodology for assessment of algorithms that correct distortions due to motion, eddy‐currents, and echo planar imaging in diffusion weighted images (DWIs). Methods The proposed ...
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  • In vivo detection of micros... In vivo detection of microscopic anisotropy using quadruple pulsed-field gradient (qPFG) diffusion MRI on a clinical scanner
    Avram, Alexandru V.; Özarslan, Evren; Sarlls, Joelle E. ... NeuroImage (Orlando, Fla.), 01/2013, Volume: 64
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    Peer reviewed
    Open access

    We report our design and implementation of a quadruple pulsed-field gradient (qPFG) diffusion MRI pulse sequence on a whole-body clinical scanner and demonstrate its ability to non-invasively detect ...
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  • Impact of time-of-day on di... Impact of time-of-day on diffusivity measures of brain tissue derived from diffusion tensor imaging
    Thomas, Cibu; Sadeghi, Neda; Nayak, Amrita ... NeuroImage (Orlando, Fla.), June 2018, 2018-06-00, 20180601, Volume: 173
    Journal Article
    Peer reviewed
    Open access

    Diurnal fluctuations in MRI measures of structural and functional properties of the brain have been reported recently. These fluctuations may have a physiological origin, since they have been ...
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