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  • Diagnosis and treatment of ... Diagnosis and treatment of high-grade astrocytoma
    Sathornsumetee, Sith; Rich, Jeremy N; Reardon, David A Neurologic clinics, 11/2007, Volume: 25, Issue: 4
    Journal Article
    Peer reviewed

    High-grade astrocytomas include the most common adult central nervous system (CNS) tumor, glioblastoma multiforme, and anaplastic astrocytoma--a highly aggressive cancer with short median survival ...
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22.
  • SB-431542, a small molecule... SB-431542, a small molecule transforming growth factor-beta-receptor antagonist, inhibits human glioma cell line proliferation and motility
    Hjelmeland, Mark D; Hjelmeland, Anita B; Sathornsumetee, Sith ... Molecular cancer therapeutics 3, Issue: 6
    Journal Article
    Peer reviewed
    Open access

    Transforming growth factor-beta (TGF-beta) is a multifunctional cytokine that promotes malignant glioma invasion, angiogenesis, and immunosuppression. Antisense oligonucleotide suppression of ...
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  • ZD6474, a novel tyrosine ki... ZD6474, a novel tyrosine kinase inhibitor of vascular endothelial growth factor receptor and epidermal growth factor receptor, inhibits tumor growth of multiple nervous system tumors
    Rich, Jeremy N; Sathornsumetee, Sith; Keir, Stephen T ... Clinical cancer research, 11/2005, Volume: 11, Issue: 22
    Journal Article
    Peer reviewed
    Open access

    Primary central nervous system (CNS) tumors represent a diverse group of tumor types with heterogeneous molecular mechanisms that underlie their formation and maintenance. CNS tumors depend on ...
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  • AAL881, a novel small molecule inhibitor of RAF and vascular endothelial growth factor receptor activities, blocks the growth of malignant glioma
    Sathornsumetee, Sith; Hjelmeland, Anita B; Keir, Stephen T ... Cancer research (Chicago, Ill.), 09/2006, Volume: 66, Issue: 17
    Journal Article
    Peer reviewed

    Malignant gliomas are highly proliferative and angiogenic cancers resistant to conventional therapies. Although RAS and RAF mutations are uncommon in gliomas, RAS activity is increased in gliomas. ...
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27.
  • Active targeting liposome-P... Active targeting liposome-PLGA composite for cisplatin delivery against cervical cancer
    Dana, Paweena; Bunthot, Suphawadee; Suktham, Kunat ... Colloids and surfaces, B, Biointerfaces, December 2020, 2020-12-00, 20201201, Volume: 196
    Journal Article
    Peer reviewed

    Display omitted •PLGA (core)/liposome (shell) nanoparticle was developed for cisplatin targeting delivery.•Physicochemical, encapsulation efficiency and drug release profiles were characterized.•This ...
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  • Differential cytokine profi... Differential cytokine profiles produced by anti-epileptic drug re-exposure of peripheral blood mononuclear cells derived from severe anti-epileptic drug patients and non-allergic controls
    Srinoulprasert, Yuttana; Kumkamthornkul, Pongsathorn; Tuchinda, Papapit ... Cytokine (Philadelphia, Pa.), September 2022, 2022-09-00, 20220901, Volume: 157
    Journal Article
    Peer reviewed

    •distinct patterns of cytokine levels between SCAR and non-SCAR PBMCs in epilepsy.•DRESS PBMCs produced different patterns of cytokine as compared to SJS/TEN PBMCs.•IL-5 and IL-13 might be a ...
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  • Designer Therapies for Glio... Designer Therapies for Glioblastoma Multiforme
    Sathornsumetee, Sith; Rich, Jeremy N. Annals of the New York Academy of Sciences, October 2008, Volume: 1142, Issue: 1
    Journal Article
    Peer reviewed

    Primary brain tumors account for less than 2% of all cancers in adults; however, they are often associated with neurologic morbidity and high mortality. Glioblastoma multiforme (GBM) has been a focus ...
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