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41.
  • Oncogenic KRAS-induced inte... Oncogenic KRAS-induced interleukin-8 overexpression promotes cell growth and migration and contributes to aggressive phenotypes of non-small cell lung cancer
    Sunaga, Noriaki; Imai, Hisao; Shimizu, Kimihiro ... International journal of cancer, 15 April 2012, Volume: 130, Issue: 8
    Journal Article
    Peer reviewed
    Open access

    The CXC chemokine interleukin‐8 (IL‐8) is an angiogenic growth factor that is overexpressed in various cancers, including non‐small cell lung cancer (NSCLC). Previously, IL‐8 was shown as a ...
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42.
  • NeuroD1 regulates survival ... NeuroD1 regulates survival and migration of neuroendocrine lung carcinomas via signaling molecules TrkB and NCAM
    Osborne, Jihan K.; Larsen, Jill E.; Shields, Misty D. ... Proceedings of the National Academy of Sciences - PNAS, 04/2013, Volume: 110, Issue: 16
    Journal Article
    Peer reviewed
    Open access

    Small-cell lung cancer and other aggressive neuroendocrine cancers are often associated with early dissemination and frequent metastases. We demonstrate that neurogenic differentiation 1 (NeuroD1) is ...
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43.
  • Identification of proteasom... Identification of proteasomal catalytic subunit PSMA6 as a therapeutic target for lung cancer
    Kakumu, Tomohiko; Sato, Mitsuo; Goto, Daiki ... Cancer science, April 2017, 2017-Apr, 20170401, Volume: 108, Issue: 4
    Journal Article
    Peer reviewed
    Open access

    To identify potential therapeutic targets for lung cancer, we performed semi‐genome‐wide shRNA screening combined with the utilization of genome‐wide expression and copy number data. shRNA screening ...
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44.
  • Growth inhibitory effects o... Growth inhibitory effects of miR‐221 and miR‐222 in non‐small cell lung cancer cells
    Yamashita, Ryo; Sato, Mitsuo; Kakumu, Tomohiko ... Cancer medicine (Malden, MA), April 2015, Volume: 4, Issue: 4
    Journal Article
    Peer reviewed
    Open access

    Both pro‐ and anti‐oncogenic roles of miR‐221 and miR‐222 microRNAs are reported in several types of human cancers. A previous study suggested their oncogenic role in invasiveness in lung cancer, ...
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45.
  • The circadian clock gene BM... The circadian clock gene BMAL1 is a novel therapeutic target for malignant pleural mesothelioma
    Elshazley, Momen; Sato, Mitsuo; Hase, Tetsunari ... International journal of cancer, 15 December 2012, Volume: 131, Issue: 12
    Journal Article
    Peer reviewed
    Open access

    Malignant pleural mesothelioma (MPM) is a highly aggressive neoplasm arising from the mesothelial cells lining the parietal pleura and it exhibits poor prognosis. Although there has been significant ...
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46.
  • Primary Liposarcoma with Ch... Primary Liposarcoma with Cholesteatoma in Mastoid
    Sato, Mitsuo P; Saito, Kazuya; Fujita, Takeshi ... The journal of international advanced otology, 04/2020, Volume: 16, Issue: 1
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    Peer reviewed
    Open access

    Liposarcoma is a soft tissue neoplasm that commonly develops in the lower extremities and rarely in the head and neck region. Herein, we report the case of a patient with primary liposarcoma that was ...
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47.
  • TIMELESS is overexpressed i... TIMELESS is overexpressed in lung cancer and its expression correlates with poor patient survival
    Yoshida, Kenya; Sato, Mitsuo; Hase, Tetsunari ... Cancer science, February 2013, Volume: 104, Issue: 2
    Journal Article
    Peer reviewed
    Open access

    TIMELESS (TIM) is a mammalian homolog of a Drosophila circadian rhythm gene, but its circadian properties in mammals have yet to be determined. TIM appears to be essential for replication protection ...
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48.
  • Pseudomembranous Invasive T... Pseudomembranous Invasive Tracheobronchial Aspergillosis with Fulminant Hepatitis and Hemophagocytic Syndrome
    Majima, Suguru; Okachi, Shotaro; Asano, Motoyo ... Internal Medicine, 2018-Aug-15, Volume: 57, Issue: 16
    Journal Article
    Peer reviewed
    Open access

    Invasive tracheobronchial aspergillosis (ITBA), a rare form of invasive pulmonary Aspergillus infection (IPA), is predominantly confined to the tracheobronchial tree. We herein report a case of ITBA ...
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  • Immortalization of human br... Immortalization of human bronchial epithelial cells in the absence of viral oncoproteins
    Ramirez, Ruben D; Sheridan, Shelley; Girard, Luc ... Cancer research (Chicago, Ill.), 12/2004, Volume: 64, Issue: 24
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    Peer reviewed
    Open access

    By expressing two genes (hTERT and Cdk4), we have developed a method to reproducibly generate continuously replicating human bronchial epithelial cell (HBEC) lines that provide a novel resource to ...
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50.
  • UHRF1, a Regulator of Methy... UHRF1, a Regulator of Methylation, as a Diagnostic and Prognostic Marker for Lung Cancer
    Goto, Daiki; Komeda, Kazuki; Uwatoko, Natsuki ... Cancer investigation, 04/2020, Volume: 38, Issue: 4
    Journal Article
    Peer reviewed

    We evaluated the value of UHRF1, a regulator of methylation, as a biomarker for lung cancer. UHRF1 is expressed at higher levels in both lung adenocarcinoma (AD) and squamous cell carcinoma (SQ); ...
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