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  • Randomized controlled trial... Randomized controlled trial of cetuximab plus chemotherapy for patients with KRAS wild-type unresectable colorectal liver-limited metastases
    Ye, Le-Chi; Liu, Tian-Shu; Ren, Li ... Journal of clinical oncology, 06/2013, Volume: 31, Issue: 16
    Journal Article
    Peer reviewed
    Open access

    To assess the effects of cetuximab plus chemotherapy as first-line treatment for unresectable colorectal liver metastases (CLMs). After resection of their primary tumors, patients with KRAS wild-type ...
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  • Modulation of miR‐29 expres... Modulation of miR‐29 expression by alpha‐fetoprotein is linked to the hepatocellular carcinoma epigenome
    Parpart, Sonya; Roessler, Stephanie; Dong, Fei ... Hepatology, September 2014, Volume: 60, Issue: 3
    Journal Article
    Peer reviewed
    Open access

    Globally, hepatocellular carcinoma (HCC) accounts for 70%‐85% of primary liver cancers and ranks as the second leading cause of male cancer death. Serum alpha‐fetoprotein (AFP), normally highly ...
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  • MicroRNA‐26a suppresses tum... MicroRNA‐26a suppresses tumor growth and metastasis of human hepatocellular carcinoma by targeting interleukin‐6‐Stat3 pathway
    Yang, Xin; Liang, Lei; Zhang, Xiao‐Fei ... Hepatology, July 2013, Volume: 58, Issue: 1
    Journal Article
    Peer reviewed
    Open access

    Down‐regulation of microRNA‐26a (miR‐26a) is associated with poor prognosis of hepatocellular carcinoma (HCC), but its functional mechanism in HCC remains unclear. In this study, we investigated the ...
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  • A unique metastasis gene si... A unique metastasis gene signature enables prediction of tumor relapse in early-stage hepatocellular carcinoma patients
    Roessler, Stephanie; Jia, Hu-Liang; Budhu, Anuradha ... Cancer research, 12/2010, Volume: 70, Issue: 24
    Journal Article
    Peer reviewed
    Open access

    Metastasis-related recurrence often occurs in hepatocellular carcinoma (HCC) patients who receive curative therapies. At present, it is challenging to identify patients with high risk of recurrence, ...
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  • MicroRNA‐26a suppresses ang... MicroRNA‐26a suppresses angiogenesis in human hepatocellular carcinoma by targeting hepatocyte growth factor‐cMet pathway
    Yang, Xin; Zhang, Xiao‐Fei; Lu, Xu ... Hepatology, 20/May , Volume: 59, Issue: 5
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    Peer reviewed
    Open access

    MicroRNA (miR)‐26a can suppress tumor growth and metastasis of hepatocellular carcinoma (HCC). Since angiogenesis is important for tumor growth and metastasis, we investigated the possible roles of ...
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  • Identification of metastasi... Identification of metastasis‐related microRNAs in hepatocellular carcinoma
    Budhu, Anuradha; Jia, Hu‐Liang; Forgues, Marshonna ... Hepatology, March 2008, Volume: 47, Issue: 3
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    Peer reviewed
    Open access

    MicroRNAs (miRNAs) have been used as cancer‐related biomarkers. Hepatocellular carcinoma (HCC) is an aggressive cancer with a dismal outcome largely due to metastasis and postsurgical recurrence. We ...
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  • Lactobacillus reuteri F‐9‐3... Lactobacillus reuteri F‐9‐35 Prevents DSS‐Induced Colitis by Inhibiting Proinflammatory Gene Expression and Restoring the Gut Microbiota in Mice
    Sun, Mao‐cheng; Zhang, Fu‐cheng; Yin, Xue ... Journal of food science, October 2018, 2018-Oct, 2018-10-00, 20181001, Volume: 83, Issue: 10
    Journal Article
    Peer reviewed

    Probiotics are considered to be a potential treatment for ulcerative colitis (UC). The aim of this study was to compare the preventive effect of a space flight‐induced mutant L. reuteri F‐9‐35 and ...
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  • Identification of microRNA‐... Identification of microRNA‐181 by genome‐wide screening as a critical player in EpCAM–positive hepatic cancer stem cells
    Ji, Junfang; Yamashita, Taro; Budhu, Anuradha ... Hepatology, August 2009, Volume: 50, Issue: 2
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    Peer reviewed
    Open access

    MicroRNAs (miRNAs) are endogenous small noncoding RNAs that regulate gene expression with functional links to tumorigenesis. Hepatocellular carcinoma (HCC) is the most common type of liver cancer, ...
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  • Transcriptomic profiling re... Transcriptomic profiling reveals hepatic stem-like gene signatures and interplay of miR-200c and epithelial-mesenchymal transition in intrahepatic cholangiocarcinoma
    Oishi, Naoki; Kumar, Mia R.; Roessler, Stephanie ... Hepatology, November 2012, Volume: 56, Issue: 5
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    Peer reviewed
    Open access

    Intrahepatic cholangiocellular carcinoma (ICC) is the second most common type of primary liver cancer. However, its tumor heterogeneity and molecular characteristics are largely unknown. In this ...
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  • Integrated Metabolite and G... Integrated Metabolite and Gene Expression Profiles Identify Lipid Biomarkers Associated With Progression of Hepatocellular Carcinoma and Patient Outcomes
    Budhu, Anuradha; Roessler, Stephanie; Zhao, Xuelian ... Gastroenterology, 05/2013, Volume: 144, Issue: 5
    Journal Article
    Peer reviewed
    Open access

    Background & Aims We combined gene expression and metabolic profiling analyses to identify factors associated with outcomes of patients with hepatocellular carcinoma (HCC). Methods We compared ...
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