Ultrazvuk (UZV) je jedan od najčešće rabljenih modaliteta oslikavanja i navođenja za intervencijske postupke infektivnih bolesti vrata i torakalnih organa. Indikacije za UZV vrata uključuju ...evaluaciju palpabilnih tvorbi vrata, slučajno pronađenih tvorbi vrata i obradu bolesnika s vrućicom nepoznatog porijekla. UZV toraksa je vrijedna metoda u procjeni aktivnosti bolesti perifernog plućnog parenhima, torakalne stijenke, dijafragme i medijastinuma. Oko 50% bolesnika sa sepsom imaju zahvaćen miokard, što je karakterizirano biventrikularnim uvećanjem, reduciranom kontraktilnošću i dijastoličkom disfunkcijom, što se može utvrditi UZV-om. Ehokardiografija je postala neinvazivna slikovna dijagnostička metoda izbora u bolesnika sa suspektnom endokardijalnom lezijom. Pokazala se korisnom ne samo za prikaz vegetativnih lezija, već i za detekciju komplikacija endokarditisa kao što su perivalvularni apsces i značajna valvularna destrukcija koja vodi do regurgitacije. Ovaj pregledni članak govori o UZV prikazu različitih patoloških stanja vrata, toraksa i srca, naglašavajući sonografske karakteristike udružene s infektivnim bolestima.
T-cell large granular lymphocytic leukemia (T-LGLL) is an uncommon but probably underdiagnosed disease caused by clonal proliferation of large granular lymphocytes. Diagnosis is typically based on ...the high number of morphologically characteristic lymphoid cells and finding of an abnormal immunophenotype by flow cytometry. Because of its relatively indolent clinical behavior, observation is often an appropriate therapy. Here we present a case of a 53-year-old male admitted to the hospital because of abdominal pain. Blood examination revealed mild mycrocitic anemia and multiplied lactate dehydrogenase level. Abdominal ultrasound showed splenomegaly of 16 cm, with no lymphadenopathy. Fine needle aspiration of bone marrow revealed hypocellular marrow with 50% of atypical lymphoid cells. There were 81% of atypical medium sized granular lymphocytes with ir-regularly shaped nuclei in peripheral blood, so the cytologic diagnosis was lymphoproliferative proc-ess. Bone marrow biopsy showed nodular and interstitial proliferation of small, partially atypical T lymphocytic cells positive for CD2, CD3, CD5, CD8, granzyme and TIA, and negative for hairy cell markers, CD10, MUM 1, bcl 1, CD4 and CD56. The finding was consistent with T-LGLL. Due to splenomegaly, the patient was treated with cyclosporine and gradually reduced dose of corticoster-oids, leading to regression of splenomegaly and normalization of lactate dehydrogenase level.
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