Machine learning (ML) models are nowadays used in complex applications in various domains, such as medicine, bioinformatics, and other sciences. Due to their black box nature, however, it may ...sometimes be hard to understand and trust the results they provide. This has increased the demand for reliable visualization tools related to enhancing trust in ML models, which has become a prominent topic of research in the visualization community over the past decades. To provide an overview and present the frontiers of current research on the topic, we present a State‐of‐the‐Art Report (STAR) on enhancing trust in ML models with the use of interactive visualization. We define and describe the background of the topic, introduce a categorization for visualization techniques that aim to accomplish this goal, and discuss insights and opportunities for future research directions. Among our contributions is a categorization of trust against different facets of interactive ML, expanded and improved from previous research. Our results are investigated from different analytical perspectives: (a) providing a statistical overview, (b) summarizing key findings, (c) performing topic analyses, and (d) exploring the data sets used in the individual papers, all with the support of an interactive web‐based survey browser. We intend this survey to be beneficial for visualization researchers whose interests involve making ML models more trustworthy, as well as researchers and practitioners from other disciplines in their search for effective visualization techniques suitable for solving their tasks with confidence and conveying meaning to their data.
Recently, artificial intelligence and machine learning in general have demonstrated remarkable performances in many tasks, from image processing to natural language processing, especially with the ...advent of deep learning (DL). Along with research progress, they have encroached upon many different fields and disciplines. Some of them require high level of accountability and thus transparency, for example, the medical sector. Explanations for machine decisions and predictions are thus needed to justify their reliability. This requires greater interpretability, which often means we need to understand the mechanism underlying the algorithms. Unfortunately, the blackbox nature of the DL is still unresolved, and many machine decisions are still poorly understood. We provide a review on interpretabilities suggested by different research works and categorize them. The different categories show different dimensions in interpretability research, from approaches that provide "obviously" interpretable information to the studies of complex patterns. By applying the same categorization to interpretability in medical research, it is hoped that: 1) clinicians and practitioners can subsequently approach these methods with caution; 2) insight into interpretability will be born with more considerations for medical practices; and 3) initiatives to push forward data-based, mathematically grounded, and technically grounded medical education are encouraged.
The joint analysis of two datasets X and Y that describe the same phenomena (e.g. the cellular state), but measure disjoint sets of variables (e.g. mRNA vs. protein levels) is currently challenging. ...Traditional methods typically analyze single interaction patterns such as variance or covariance. However, problem-tailored external knowledge may contain multiple different information about the interaction between the measured variables. We introduce MIASA, a holistic framework for the joint analysis of multiple different variables. It consists of assembling multiple different information such as similarity vs. association, expressed in terms of interaction-scores or distances, for subsequent clustering/classification. In addition, our framework includes a novel qualitative Euclidean embedding method (qEE-Transition) which enables using Euclidean-distance/vector-based clustering/classification methods on datasets that have a non-Euclidean-based interaction structure. As an alternative to conventional optimization-based multidimensional scaling methods which are prone to uncertainties, our qEE-Transition generates a new vector representation for each element of the dataset union X union Y in a common Euclidean space while strictly preserving the original ordering of the assembled interaction-distances. To demonstrate our work, we applied the framework to three types of simulated datasets: samples from families of distributions, samples from correlated random variables, and time-courses of statistical moments for three different types of stochastic two-gene interaction models. We then compared different clustering methods with vs. without the qEE-Transition. For all examples, we found that the qEE-Transition followed by Ward clustering had superior performance compared to non-agglomerative clustering methods but had a varied performance against ultrametric-based agglomerative methods. We also tested the qEE-Transition followed by supervised and unsupervised machine learning methods and found promising results, however, more work is needed for optimal parametrization of these methods. As a future perspective, our framework points to the importance of more developments and validation of distance-distribution models aiming to capture multiple-complex interactions between different variables.
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