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Primarni vaskulitis osrednjega živčevja, omejen na možgansko deblo = Primary vasculitis of the CNS restricted to the brainstemPolenčič, Aljoša ; Popović, Mara ; Vodušek, David B.Background. Primary or isolated vasculitis of the central nervous system (PVCNS) is a rare disease with an atypical clinical picture. It involves both small and mediumsized leptomeningeal, cortical ... and subcortical vessels. Etiology and pathogenesis are unknown. The first clinical sign is usually a headache and later in the disease virtually every neurological symptom and sign has been reported. The golden standard for diagnosis is a biopsy. High doses of corticosteroids and cyclophosphamide have been recommended for treatment. Patient and methods. A case of a 61 years old women with diabetes and hypertension is reported. She sudenly developed signs of focal ischemic brain stem lesion and had lesions visualised on MR in brain stem and both hemisfers. After temporary remission she developed similar signs five months later. She had died before the diagnostic procedures were performed. The diagnosis of PVCNS isolated to the brain stem was made post mortem. Conclusions. The diagnostic and therapeutic challenges of PVCNS are big even for an experienced clinician. Diagnosis depends on a combination of clinical, imaging and histological features. Often the diagnosis is confirmed post mortem.Source: Zdravniški vestnik : glasilo Slovenskega zdravniškega društva = Slovenian medical journal = journal of Slovenian Medical Association. - ISSN 1318-0347 (Letn. 74, št. 7-8, 2005, str. 435-438)Type of material - article, component partPublish date - 2005Language - slovenianCOBISS.SI-ID - 20212953
Author
Polenčič, Aljoša |
Popović, Mara |
Vodušek, David B.
Topics
Cerebral Artery Diseases |
Diagnosis |
Pathology |
Drug Therapy |
Vasculitis |
Cerebral Angiography |
Middle Age |
Biopsy |
Cerebralna angiografija |
Vaskulitis |
Biopsija |
Srednja leta
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source: Zdravniški vestnik : glasilo Slovenskega zdravniškega društva = Slovenian medical journal = journal of Slovenian Medical Association. - ISSN 1318-0347 (Letn. 74, št. 7-8, 2005, str. 435-438)
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Polenčič, Aljoša | ![]() |
Popović, Mara | 07090 |
Vodušek, David B. | 07476 |
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