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Kvantitativna analiza parnih HRCT posnetkov v vdihu in izdihu pri bolnikih s KOPB; primerjava s testi pljučne funkcije : magistrsko deloPožek, IgorBACKGROUND: Chronic obstructive pulmonary disease (COPD), including chronic bronchitis and emphysema is characterized by progresive airway obstruction that is not fully reversible with the ... administration of bronchodilator drugs. Computed tomography (CT) is an established tool for in vivo assessment of pulmonary emphysema, which spears as areas of decreased lung attenuation. Despite numerous investigations, the morphologic evaluation of COPD by HRCT has not yet been fully standardized. Expiratory CT can reveal air trapping in the lungs, but which method is the most accurate in predicting pulmonary function tests (PFT) is not yet known. AIMS: We tried to find out correaltion between attenuation measurements of the lung on inspiratory and expiratory scans and pulmonary function tests (PFT) in patients with COPD. Influence of regional distribution of emphysema on PFT and value of paired inspiratory/expiratory CT scans in prediction of PFT in patients with COPD wasalso evaluated. SUBJECTS AND METHODS: Thirtytwo current or ex smokers with COPD underwent inspiratory and expiratory CT scans and PFTs. Three scan pairs (in the upper, middle and lower lung fields) were evaluated by densito- and planimetry using dedicated software. Two emphysema indexes (EI -950 and EI -900), mean lung density (MLD) and cross-sectional lung area were measured. Change in cross-sectional lung area at inspiration and expiration (area reduction score-ARS), ratio of emphysema indexes at inspiration and expirationand ratio and difference between MLD at inspiration and expiration were calculated. All measurements were correlated with results of PFTs. (Abstract truncated at 2000 characters)Type of material - master's thesisPublication and manufacture - Ljubljana : [I.Požek], 2006Language - slovenianCOBISS.SI-ID - 22359001
Author
Požek, Igor
Other authors
Košnik, Mitja |
Fležar, Matjaž
Topics
Lung Diseases, Obstructive |
Tomography, X-Ray Computed |
Methods |
Lung Volume Measurements |
Pulmonary Emphysema |
Bronchitis |
Pulmonary Diffusing Capacity |
Forced Expiratory Flow Rates |
Vital Capacity |
Forced Expiratory Volume |
Pulmonary disease, chronic obstructive |
Diagnosis |
Pulmonary disease, chronic obstructive |
Physiopathology |
Respiratory function tests |
Diagnosis |
Bronhitis |
Pljučne bolezni obstruktivne |
Pljučni emfizem |
Pljučni volumen, meritve |
Tomografija radiografska, računalniška |
Računalniška tomografija |
Metode |
Forsirani, ekspiratorni pretoki |
Forsirani, ekspiratorni volumen |
Pljučna, difuzijska kapaciteta |
Vitalna kapaciteta |
Kronična obstruktivna pljučna bolezen |
Diagnostika |
Kronična obstruktivna pljučna bolezen |
Patofiziologija |
Respiratorni funkcijski testi |
Diagnostika |
pulmologija |
radiologija
Library | Call number – location, accession no. ... | Copy status |
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MF, Central Medical Library, Lj. | magistrske naloge POŽEK Igor Kvantitativna IN: 020070338 |
available - outside loan, loan period: 1 months |
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Database name | Field | Year |
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Links to authors' personal bibliographies | Links to information on researchers in the SICRIS system |
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Požek, Igor | 25176 |
Košnik, Mitja | 10921 |
Fležar, Matjaž | 15710 |
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