The manuscript discusses about the evidence linking physical inactivity with overweight and obesity. The hypothesis is that low levels of physical activity and sedentary lifestyles favour positive ...energy balance, therefore leading to obesity low grade inflammation and weight gain. Based on body mass index (BMI) the percentage of fat mass and waist circumference, the participants were divided in overweight and normal weight group. Anthropometric parameters, biochemical variable C-reactive protein (CRP) and serum visfatin and life style factors were compared between the studied groups using Student's t-test. On relating BMI with the various lifestyle factors, a statistically significant difference regarding physical activity, physical fitness and biochemical parameters were found between studied groups. Conclusion: The increasing prevalence of physical inactivity seems to be an important explanation for increasing obesity related disorders.
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