Journal of organic chemistry,
11/2021, Volume:
86, Issue:
21
Journal Article
The multiple C-H bonds of biaryl ynones render the 6-exo-trig regioselective C-H activation dearomatization to spiro5.5trienones challenging since the competing reactions of C-H bonds on Ar
or the
-C-H bonds on Ar
may result in 5-exo-trig cyclization to indenones or 6-exo-trig
-dearomatization, respectively. We here report an unprecendented dearomatization of biaryl ynones with aldehydes via double C-H functionalization where a regiospecific remote unactivated
-C-H functionalization of biaryl ynones efficiently furnishes acylated spiro5.5trienones. This cascade cyclization features a green catalyst and solvent and high atom- and step-economy.
It was not necessary to add the material to the shelf.
Bibliographic material was successfully added on shelf.
Adding bibliographical material on shelf was not successful.
Material is already on the shelf.
Permalink
URL:
Impact factor
Access to the JCR database is permitted only to users from Slovenia. Your current IP address is not on the list of IP addresses with access permission, and authentication with the relevant AAI accout is required.
Year
Impact factor
Edition
Category
Classification
JCR
SNIP
JCR
SNIP
JCR
SNIP
JCR
SNIP
Select the library membership card:
DRS,
in which the journal is indexed
Database name
Field
Year
Links to authors' personal bibliographies
Links to information on researchers in the SICRIS system
