E-resources
-
Guan, Wei-Jie; Liang, Wen-Hua; Zhao, Yi; Liang, Heng-Rui; Chen, Zi-Sheng; Li, Yi-Min; Liu, Xiao-Qing; Chen, Ru-Chong; Tang, Chun-Li; Wang, Tao; Ou, Chun-Quan; Li, Li; Chen, Ping-Yan; Sang, Ling; Wang, Wei; Li, Jian-Fu; Li, Cai-Chen; Ou, Li-Min; Cheng, Bo; Xiong, Shan; Ni, Zheng-Yi; Xiang, Jie; Hu, Yu; Liu, Lei; Shan, Hong; Lei, Chun-Liang; Peng, Yi-Xiang; Wei, Li; Liu, Yong; Hu, Ya-Hua; Peng, Peng; Wang, Jian-Ming; Liu, Ji-Yang; Chen, Zhong; Li, Gang; Zheng, Zhi-Jian; Qiu, Shao-Qin; Luo, Jie; Ye, Chang-Jiang; Zhu, Shao-Yong; Cheng, Lin-Ling; Ye, Feng; Li, Shi-Yue; Zheng, Jin-Ping; Zhang, Nuo-Fu; Zhong, Nan-Shan; He, Jian-Xing
The European respiratory journal, 05/2020, Volume: 55, Issue: 5Journal Article
The coronavirus disease 2019 (COVID-19) outbreak is evolving rapidly worldwide. To evaluate the risk of serious adverse outcomes in patients with COVID-19 by stratifying the comorbidity status. We analysed data from 1590 laboratory confirmed hospitalised patients from 575 hospitals in 31 provinces/autonomous regions/provincial municipalities across mainland China between 11 December 2019 and 31 January 2020. We analysed the composite end-points, which consisted of admission to an intensive care unit, invasive ventilation or death. The risk of reaching the composite end-points was compared according to the presence and number of comorbidities. The mean age was 48.9 years and 686 (42.7%) patients were female. Severe cases accounted for 16.0% of the study population. 131 (8.2%) patients reached the composite end-points. 399 (25.1%) reported having at least one comorbidity. The most prevalent comorbidity was hypertension (16.9%), followed by diabetes (8.2%). 130 (8.2%) patients reported having two or more comorbidities. After adjusting for age and smoking status, COPD (HR (95% CI) 2.681 (1.424-5.048)), diabetes (1.59 (1.03-2.45)), hypertension (1.58 (1.07-2.32)) and malignancy (3.50 (1.60-7.64)) were risk factors of reaching the composite end-points. The hazard ratio (95% CI) was 1.79 (1.16-2.77) among patients with at least one comorbidity and 2.59 (1.61-4.17) among patients with two or more comorbidities. Among laboratory confirmed cases of COVID-19, patients with any comorbidity yielded poorer clinical outcomes than those without. A greater number of comorbidities also correlated with poorer clinical outcomes.
Author
Shelf entry
Permalink
- URL:
Impact factor
Access to the JCR database is permitted only to users from Slovenia. Your current IP address is not on the list of IP addresses with access permission, and authentication with the relevant AAI accout is required.
Year | Impact factor | Edition | Category | Classification | ||||
---|---|---|---|---|---|---|---|---|
JCR | SNIP | JCR | SNIP | JCR | SNIP | JCR | SNIP |
Select the library membership card:
If the library membership card is not in the list,
add a new one.
DRS, in which the journal is indexed
Database name | Field | Year |
---|
Links to authors' personal bibliographies | Links to information on researchers in the SICRIS system |
---|
Source: Personal bibliographies
and: SICRIS
The material is available in full text. If you wish to order the material anyway, click the Continue button.