Biokemijske metode probira za preeklampsiju

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Biokemijske metode probira za preeklampsiju

Đelmiš, Josip

Gynaecologia et perinatologia (Zagreb, Croatia), 01/2019, Volume: 28, Issue: 1-2

Journal Article

Određivanje placentnog čimbenika rasta (PlGF) i topljivog receptora sFlt-1 omogućuju sami ili zajedno dijagnozu preeklampsije prije pojave kliničkih simptoma, hipertenzije i proteinurije. Članak je usredotočen na rezultate dobivene u istraživanjima o utjecaju angiogenih i antiangiogenih čimbenike na razvoj preeklampsije. Dostupni rezultati pokazuju da se angiogeni i antiangiogeni čimbenici, posebice, sFlt-1 i PlGF-a, mogu smatrati biomarkerima s najboljim dijagnostičkim učinkom. Visok omjer topljivog receptora Flt-1 i placentnog čimbenika rasta (PlGF) je dobar predskazatelj preeklampsije.

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