Purpose To evaluate the optical quality of the Visian Implantable Collamer Lens (ICL) for different powers and pupil diameters. Methods Wavefront aberrations of the −3, −6, −9, −12 and −15 diopters (D) V4b ICLs were measured at 3- and 4.5-mm pupils. The root mean square (RMS) of total higher order aberrations (HOAs), trefoil, coma, tetrafoil, secondary astigmatism, and spherical aberration were evaluated. In addition, modulation transfer function (MTF) of the five ICL powers was measured for a 3-mm pupil. The point spread functions (PSFs) of each ICL evaluated was calculated from the wavefront aberrations at 4.5-mm pupil. Results The ICLs evaluated had negative spherical aberration and negligible amounts of other aberrations. The negative spherical aberration increases when the ICL power increases being related with its innate optical properties. At 3-mm pupil, no statistically significant differences between ICLs were found for all the Zernike coefficient RMS values analyzed ( p  > 0.05). At 4.5-mm pupil, significant RMS values for the spherical aberration and total HOAs were found between medium-low and high powers ( p  < 0.05). Similar MTFs were obtained for all ICLs, although they slightly worsened when increased the ICL power. Conclusions ICLs evaluated provide good optical quality in terms of wavefront aberrations, MTF, and PSF. Although spherical aberration increases with ICL power, these values are clinically negligible to affect the visual quality after its implantation.