To explore the willingness to participate in genomics research among African Americans, we developed a technique specifically suited to a relaxed social setting. The “Qualitative Story Deck,” (QSD) is a gamified, structured elicitation technique that allows for the spontaneous creation of scenarios with variable attributes. We used the QSD to create research scenarios that varied on four details (race/ethnicity of the researcher, research goal, biospecimen requested, and institutional affiliation). Participants created scenarios by randomly choosing cards from these categories and provided: (1) a judgment about their willingness to participate in the research project represented; and (2) their thought process in reaching a decision. The QSD has applicability to topics involving decision making or in cases where it would be beneficial to provide vignettes with alternate attributes. Additional benefits include rapid rapport building, applicability to little known or sensitive topics, and suitability for both qualitative and quantitative analyses.