As a “plug-and-play” nuclear system, the technology of fission battery enables nuclear reactor systems to function as batteries. Undoubtedly, advanced intelligent technologies have to be adopted to realize the excellent attributes of fission batteries, i.e., economic, standardized, installed, unattended, and reliable, and its commercial applications. This article proposed the edge-cloud collaboration technology for fission batteries to satisfy its intelligent requirements. A detailed framework for a fission battery management system has been developed. To develop such a management system, four types of concrete transmission information for the edge-cloud collaboration (i.e. resource and data, AI technologies, application and services, safety and strategies) are identified. The edge and cloud designs are also discussed in detail, including their hardware and software. A functional framework of edge-cloud collaboration network platform for fission battery management system is developed preliminarily. The framework is based on a three-layer structure, i.e., perception layer, technical layer and application layer. Although no detailed algorithm or verification is introduced (since the edge-cloud collaboration framework has been widely used in some industry fields but not in nuclear engineering), as primarily work for the future detailed study of fission battery, it is necessary and extremely important.