Intravenous cyclophosphamide in refractory polyneuropathy associated with IgM monoclonal gammopathy: An uncontrolled open trial

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$Intravenous cyclophosphamide in refractory polyneuropathy associated with IgM monoclonal gammopathy: An uncontrolled open trial$

Intravenous cyclophosphamide in refractory polyneuropathy associated with IgM monoclonal gammopathy: An uncontrolled open trial

Hamidou, Mohamed A.; Belizna, Cristina; Wiertlewsky, Sandrine; Audrain, Marie; Biron, Charlotte; Grolleau, Jean-Yves; Mussini, Jean-Marie

The American journal of medicine, 04/2005, Volume: 118, Issue: 4

Journal Article

Monoclonal gammopathy-associated demyelinating neuropathy is a common and probably under-recognized peripheral neuropathy in elderly patients. The presence of serum anti-myelin-associated glycoprotein antibodies, immunoglobulin M and complement deposits on the myelin sheaths, as well as animal models, favor an immune-mediated disease supporting the use of immune therapies.

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