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Teles e Oliveira, Deylane Menezes; Marroquim, Mário Sérgio Coelho; de Serpa Brandão, Rafael Melo Santos; da Mata Sousa, Luiz Claudio Demes; das Chagas Alves Lima, Francisco; do Monte, Semiramis Jamil Hadad; de Sousa Lima, Antonio Vanildo; Coelho, Antonio Gilberto Borges; Costa, Jhonatan Matheus Sousa; Ramos, Ricardo Martins; Miranda Pereira, Ester; da Silva, Adalberto Socorro
Human immunology, January 2021, 2021-Jan, 2021-01-00, 20210101, Volume: 82, Issue: 1Journal Article
To improve the availability of three-dimensional (3D) structures of HLA molecules, we created the pHLA3D database. In its first version, we modeled and published 106 3D structures of HLA class I molecules from the HLA-A, HLA-B, and HLA-C loci. This paper presents an update of this database, providing more 127 3D structures of HLA class II molecules (41 DR, 42 DQ, and 44 DP), predicted via homology modeling with MODELLER and SWISS-MODEL. These new 3D structures of HLA class II molecules are now freely available at pHLA3D (www.phla3d.com.br) for immunologists and other researchers working with HLA molecules.
