E-resources
-
González‐Mariño, Iria; Baz‐Lomba, Jose Antonio; Alygizakis, Nikiforos A.; Andrés‐Costa, Maria Jesús; Bade, Richard; Barron, Leon P.; Been, Frederic; Berset, Jean‐Daniel; Bijlsma, Lubertus; Bodík, Igor; Brenner, Asher; Brock, Andreas L.; Burgard, Daniel A.; Castrignanò, Erika; Christophoridis, Christophoros E.; Covaci, Adrian; Voogt, Pim; Devault, Damien A.; Dias, Mário J.; Emke, Erik; Fatta‐Kassinos, Despo; Fedorova, Ganna; Fytianos, Konstantinos; Gerber, Cobus; Grabic, Roman; Grüner, Stefan; Gunnar, Teemu; Hapeshi, Evroula; Heath, Ester; Helm, Björn; Hernández, Félix; Kankaanpaa, Aino; Karolak, Sara; Kasprzyk‐Hordern, Barbara; Krizman‐Matasic, Ivona; Lai, Foon Yin; Lechowicz, Wojciech; Lopes, Alvaro; López de Alda, Miren; López‐García, Ester; Löve, Arndís S. C.; Mastroianni, Nicola; McEneff, Gillian L.; Montes, Rosa; Munro, Kelly; Nefau, Thomas; Oberacher, Herbert; O'Brien, Jake W.; Olafsdottir, Kristin; Picó, Yolanda; Plósz, Benedek G.; Polesel, Fabio; Postigo, Cristina; Quintana, José Benito; Ramin, Pedram; Reid, Malcolm J.; Rice, Jack; Rodil, Rosario; Senta, Ivan; Simões, Susana M.; Sremacki, Maja M.; Styszko, Katarzyna; Terzic, Senka; Thomaidis, Nikolaos S.; Thomas, Kevin V.; Tscharke, Ben J.; Nuijs, Alexander L. N.; Yargeau, Viviane; Zuccato, Ettore; Castiglioni, Sara; Ort, Christoph
Addiction (Abingdon, England), January 2020, Volume: 115, Issue: 1Journal Article
Background and aims Wastewater‐based epidemiology is an additional indicator of drug use that is gaining reliability to complement the current established panel of indicators. The aims of this study were to: (i) assess spatial and temporal trends of population‐normalized mass loads of benzoylecgonine, amphetamine, methamphetamine and 3,4‐methylenedioxymethamphetamine (MDMA) in raw wastewater over 7 years (2011–17); (ii) address overall drug use by estimating the average number of combined doses consumed per day in each city; and (iii) compare these with existing prevalence and seizure data. Design Analysis of daily raw wastewater composite samples collected over 1 week per year from 2011 to 2017. Setting and Participants Catchment areas of 143 wastewater treatment plants in 120 cities in 37 countries. Measurements Parent substances (amphetamine, methamphetamine and MDMA) and the metabolites of cocaine (benzoylecgonine) and of Δ9‐tetrahydrocannabinol (11‐nor‐9‐carboxy‐Δ9‐tetrahydrocannabinol) were measured in wastewater using liquid chromatography–tandem mass spectrometry. Daily mass loads (mg/day) were normalized to catchment population (mg/1000 people/day) and converted to the number of combined doses consumed per day. Spatial differences were assessed world‐wide, and temporal trends were discerned at European level by comparing 2011–13 drug loads versus 2014–17 loads. Findings Benzoylecgonine was the stimulant metabolite detected at higher loads in southern and western Europe, and amphetamine, MDMA and methamphetamine in East and North–Central Europe. In other continents, methamphetamine showed the highest levels in the United States and Australia and benzoylecgonine in South America. During the reporting period, benzoylecgonine loads increased in general across Europe, amphetamine and methamphetamine levels fluctuated and MDMA underwent an intermittent upsurge. Conclusions The analysis of wastewater to quantify drug loads provides near real‐time drug use estimates that globally correspond to prevalence and seizure data.
Author
Shelf entry
Permalink
- URL:
Impact factor
Access to the JCR database is permitted only to users from Slovenia. Your current IP address is not on the list of IP addresses with access permission, and authentication with the relevant AAI accout is required.
Year | Impact factor | Edition | Category | Classification | ||||
---|---|---|---|---|---|---|---|---|
JCR | SNIP | JCR | SNIP | JCR | SNIP | JCR | SNIP |
Select the library membership card:
If the library membership card is not in the list,
add a new one.
DRS, in which the journal is indexed
Database name | Field | Year |
---|
Links to authors' personal bibliographies | Links to information on researchers in the SICRIS system |
---|
Source: Personal bibliographies
and: SICRIS
The material is available in full text. If you wish to order the material anyway, click the Continue button.