Tourist engagement (TE) has gained prominence in academia and industry. While previous studies have focused on exploring TE in tourism and hospitality, no consolidated empirical study has been conducted. We conducted a comprehensive meta-analysis using data from 73 independent studies retrieved from 72 papers, with a total sample size of 41,757. Our analysis, using meta-analytic structural equation modelling, tested a conceptual framework and found that tourist experience and TE individually mediate tourists’ satisfaction, emotion, behavioral intention, and loyalty. Additionally, cultural (e.g., power distance, individualism, uncertainty avoidance, indulgence) and economic (e.g., human development index) moderators influence TE. Our findings also suggest that popular global destinations enhance the relationship between tourist experience, engagement, and behavioral intention.