The problem of fuzzy observer-based controller design is investigated for nonlinear networked control systems subject to imperfect communication links and parameter uncertainties. The nonlinear networked control systems with parameter uncertainties are modeled through an interval type-2 (IT2) Takagi-Sugeno (T-S) model, in which the uncertainties are handled via lower and upper membership functions. The measurement loss occurs randomly, both in the sensor-to-observer and the controller-to-actuator communication links. Specially, a novel data compensation strategy is adopted in the controller-to-actuator channel. The observer is designed under the unmeasurable premise variables case, and then, the controller is designed with the estimated states. Moreover, the conditions for the existence of the controller can ensure that the resulting closed-loop system is stochastically stable with the predefined disturbance attenuation performance. Two examples are provided to illustrate the effectiveness of the proposed method.