E-resources
Peer reviewed
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Morisaki, Naoko; Morita, Koji; Nishikawa, Asuka; Nakatsu, Noriyuki; Fukui, Yasuhisa; Hashimoto, Yuichi; Shirai, Ryuichi
Tetrahedron, 04/2000, Volume: 56, Issue: 17Journal Article
Phosphatidylinositol analogs (PI C2–PI C18) having a series of saturated fatty acid (C2–C18) at sn-2 position were synthesized and subjected to the phosphorylation reaction with phosphatidylinositol 3-kinase (PI 3-kinase). The reactivity of PI C8 with PI 3-kinase turned out to be comparable to that of natural PI, although PI C18 was not phosphorylated under the same condition. The chirality of sn-2 center was not responsible for the phosphorylation reaction.
