The human neck is one of the most thermally sensitive body regions to nociceptive stimuli. Neck cooling has been extensively researched to improve athletic performance in the heat. However, there has been very little research into the use of conductive neck cooling for indoor thermal comfort. We thereby designed three ultralight cooling collars with cooling gels or phase change materials (GEL6, PCM15, and PCM18). Their cooling performance on thermal comfort enhancement of 14 healthy young female participants under two warm indoor temperatures (28 °C and 30 °C) was investigated. Thermophysiological and perceptual responses, including skin temperature, heart rate, sweating, thermal sensation vote (TSV), thermal comfort vote (TCV), and thermal preference vote (TPV), were extensively studied. Results showed that, in contrast to GEL6, PCM15 and PCM18 significantly decreased the neck skin temperature, with PCM15 exhibiting the greatest reduction of 4.37 °C at 28 °C. PCM15 and PCM18 significantly decreased overall and local TSVs while also increasing overall and local TCVs (all p < 0.05), thus they could maintain >80 % occupant satisfaction at 28 °C. At 30 °C indoor temperature, however, none of these three cooling collars were found to meet the 80 % occupant satisfaction criterion. When compared to GEL6, PCM15 and PCM18 were found to only significantly reduce local TSVs at the head and neck (all p < 0.05). In sum, PCM15 and PCM18 have the potential to increase acceptable HVAC summer cooling setpoint temperature by 2.5 °C, from 25.5 °C to 28.0 °C, leading to a 25 % reduction in building cooling energy consumption. Display omitted •Cooling gels failed to maintain occupant thermal comfort at 28 and 30 °C temperatures.•Cooling collars PCM15 & PCM18 could maintain >80 % occupant satisfaction at 28 °C.•All cooling collars failed to meet the 80 % occupant satisfaction at 30 °C temperature. The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.•PCM15 and PCM18 extended acceptable HVAC cooling setpoint temperature by 2.5 °C.