...the evaluation of the safety of a novel nanodevice is a process that should start at the very first step of concept and design. The submitted works were expected to feature innovative areas such as nanomaterials applied in biotechnology; nanoparticles used in environmental science and technology; nanosensors used in biosystems; nanomedicine in the context of biochemical engineering; micro- and nanofluidics; micro- and nano-electromechanical systems; nanoscience and nanotoxicology; nanotechnology applied in biology, medicine, food, environmental and agriculture sectors; environmental engineering and chemical engineering; nanoscale electrochemisty in biotechnology; computational nanochemistry in biotechnology; and life cycle assessment of nanobiotechnology. ...the review summarizes the use of nanotechnology in self-assembly methods and the challenges to adapt these nanomaterials to commercial applications. ...party material in this article could be subject to other licenses (typically indicated in the credit line), and in this case, users are required to obtain permission from the license holder to reuse the material.