Baffles with holes in different diameters (or HDD baffles) and conically-corrugated tubes are respectively longitudinal flow baffle and high-efficiency heat exchange tubes proposed by the author. In this paper, vibrations of tube bundles with HDD baffles and fluid flow as well as heat transfer inside conically-corrugated tubes were numerically simulated, and the heat exchanger with conically-corrugated tubes and HDD baffles was tested for the heat transfer efficiency. It is found that compared with the traditional segmental baffles, tube bundle vibrations in heat exchangers, if using the HDD baffles, can be significantly reduced. Regarding heat transfer efficiency, conically-corrugated tubes are much better than smooth tubes and even better than other high-efficiency heat transfer tubes. Compared with the traditional heat exchangers, heat exchangers constructed with conically-corrugated tubes and the HDD baffles can provide better heat transfer efficiency and less tube bundle vibration.