Abstract Doping is a well-known strategy to enhance the electrochemical energy storage performance of layered cathode materials. Many studies on various dopants have been reported; however, a general relationship between the dopants and their effect on the stability of the positive electrode upon prolonged cell cycling has yet to be established. Here, we explore the impact of the oxidation states of various dopants (i.e., Mg 2+ , Al 3+ , Ti 4+ , Ta 5+ , and Mo 6+ ) on the electrochemical, morphological, and structural properties of a Ni-rich cathode material (i.e., LiNi 0.91 Co 0.09 O 2 ). Galvanostatic cycling measurements in pouch-type Li-ion full cells show that cathodes featuring dopants with high oxidation states significantly outperform their undoped counterparts and the dopants with low oxidation states. In particular, Li-ion pouch cells with Ta 5+ - and Mo 6+ -doped LiNi 0.91 Co 0.09 O 2 cathodes retain about 81.5% of their initial specific capacity after 3000 cycles at 200 mA g −1 . Furthermore, physicochemical measurements and analyses suggest substantial differences in the grain geometries and crystal lattice structures of the various cathode materials, which contribute to their widely different battery performances and correlate with the oxidation states of their dopants.