The cost of storing and transporting hydrogen have been one of the main challenges for the realization of the hydrogen economy. Liquid organic hydrogen carriers (LOHC) are a promising novel solution to tackle these challenges. In this paper we compare the LOHC concept to compressed gas truck delivery and on-site production of hydrogen via water electrolysis. As a case study we consider transportation of by-product hydrogen from chlor-alkali and chlorate plants to a single industrial customer, which was considered to have the greatest potential for the LOHC technology to enter the markets. The results show that the LOHC delivery chain could significantly improve the economics of long distance road transport. For economic feasibility, the most critical parameters identified are the heat supply method for releasing hydrogen at the end-user site and the investment costs for LOHC reactors. Display omitted •Techno-economic model for point-to-point large scale road transport of hydrogen.•The LOHC concept can decrease long-distance delivery costs significantly.•Heat supply method for dehydrogenation and heat integration are key.•Utilization of waste heat can reduce costs by 40%.