The construction of information-based leadership is of great practical significance in driving the development of higher education. By giving full play to the application advantages of modern information technology, an educational system covering all levels of higher education is constructed, we will comprehensively improve the level of informationization and intellectualization of higher education, and help to realize high-quality development of higher education. This paper analyzes the role of modern information technology in improving the leadership of information-based education in colleges and universities, and puts forward some relevant strategies to improve the leadership of information-based education in colleges and universities by using modern information technology.