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  • Practical synthesis and application of halogen-doped pyrrole building blocks [Elektronski vir]
    Cotman, Andrej Emanuel ...
    A practical access to four new halogen-substituted pyrrole building blocks was realized in two to five synthetic steps from commercially available starting materials. The target compounds were ... prepared on a 50 mg to 1 g scale, and their conversion to nanomolar inhibitors of bacterial DNA gyrase B was demonstrated for three of the prepared building blocks to showcase the usefulness of such chemical motifs in medicinal chemistry.
    Vir: ACS omega [Elektronski vir]. - ISSN 2470-1343 (Vol. 6, no. 14, 2021, str. 9723-9730)
    Vrsta gradiva - e-članek ; neleposlovje za odrasle
    Leto - 2021
    Jezik - angleški
    COBISS.SI-ID - 58134275

    Povezava(-e):

    https://pubs.acs.org/doi/10.1021/acsomega.1c00331
    https://pubs.acs.org/doi/pdf/10.1021/acsomega.1c00331
    DOI

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