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Fakulteta za farmacijo, Ljubljana (FFALJ)
  • Peripheral arterial tonometry and angiogenic biomarkers in preeclampsia [Elektronski vir]
    Kumer, Kristina ...
    Objective: To evaluate changes in vascular function and serum biomarkers in women with and without preeclampsia (PE) to create a model for the easier and more precise diagnosis of PE in the future. ... Methods: Endothelial function and arterial stiffness were evaluated using peripheral arterial tonometry and concentrations of placental growth factor (PlGF), soluble fms like tyrosine kinase 1 (sFlt-1) and soluble endoglin (sEng) were determined by immunoassay. Results: Arterial stiffness deteriorates and endothelial function is better in women with PE compared with a healthy pregnancy. Women who developed PE had a decreased PlGF and PlGF/(sFlt-1+ sEng) ratio and an increased sEng, and sFlt-1/PlGF ratio. Conclusion: Peripheral arterial analysis did provide additional information beyond serum biomarkers in the diagnosis of PE.
    Vir: Hypertension in pregnancy. - ISSN 1525-6065 (Vol. 37, iss. 4, Nov. 2018, str. 197-203)
    Vrsta gradiva - e-članek
    Leto - 2018
    Jezik - angleški
    COBISS.SI-ID - 4612721

    Povezava(-e):

    https://www.tandfonline.com/doi/full/10.1080/10641955.2018.1524478

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