Novejši pogledi na tuberkulinski test = Tuberculin test - new aspects
Skralovnik-Štern, Aleksandra ...
Host immunity plays an important role in the host-pathogen interaction occuring in persons exposed to Mycobacterium tuberculosis. In the last few years, numerous in vitro studies made it possible to ...define the type and number of cells which produce cytokines, the interactions between them and to reveal the concentrations in which cytokines are produced. In clinical practice there is a recognized need for a better, faster, more sensitive and evaluable in vitro tuberculin test which would require no return visit for skin test reading and no painful local reactions. In 11 healthy persons, interferon gamma assay and a novel CD 69 antigen determination after stimulation of whole blood with PPD correlate with their tuberculin skin tests. It takes only 24 hours to obtain the results. Blast transformation test, the fundamental test for the evaluation of the role of lymphocytes in vitro, also correlates with the interferon gamma assay and CD 69 antigen determination. Further studies are planned to adress the issue of sensitivity and specificity, especially in immunosupressed patients (these are patients after transplantation, those receiving immunosupressive drugs and those infected with HIV). Systemic effects of tuberculin, well known from Koch's experiments with intradernal challenge of tuberculosis patients with large quantities of tuberculin, are of interest again. Booster effect - the phenomenon of increased tuberculin skin reaction upon retesting after a few days - is believed to result from the reactivation of the preexisting delayed type hypersensitivity and indicates the systemic effects of tuberculin skin tests which are believed to be safe and often repeatable.
Bibliografsko gradivo je bilo uspešno dodano na polico.
Dodajanje bibliografskega gradiva na polico ni uspelo.
Gradivo je že na polici.
Trajna povezava
URL:
Faktor vpliva
Dostop do baze podatkov JCR je dovoljen samo uporabnikom iz Slovenije. Vaš trenutni IP-naslov ni na seznamu dovoljenih za dostop, zato je potrebna avtentikacija z ustreznim računom AAI.
Leto
Faktor vpliva
Izdaja
Kategorija
Razvrstitev
JCR
SNIP
JCR
SNIP
JCR
SNIP
JCR
SNIP
Izberite knjižnično izkaznico:
Baze podatkov,
v katerih je revija indeksirana
Ime baze podatkov
Področje
Leto
Povezave do osebnih bibliografij avtorjev
Povezave do podatkov o raziskovalcih v sistemu SICRIS
Storitev za pridobivanje naslova trenutno ni dostopna, prosimo, poskusite še enkrat.
S klikom na gumb "V redu" boste potrdili zgoraj izbrano prevzemno mesto in dokončali postopek rezervacije.
S klikom na gumb "V redu" boste potrdili zgoraj izbrano prevzemno mesto in naslov za dostavo ter dokončali postopek rezervacije.
S klikom na gumb "V redu" boste potrdili zgoraj izbrani naslov za dostavo in dokončali postopek rezervacije.
Obvestilo
Trenutno je storitev za avtomatsko prijavo in rezervacijo nedostopna. Gradivo lahko rezervirate sami na portalu Biblos ali ponovno poskusite tukaj kasneje.
Citiranje
Funkcionalnost trenutno ni na voljo. Prosimo, poskusite kasneje.
Naročanje gradiva za izposojo v čitalnice
Naročanje kopij člankov
Urnik dostave gradiva z oznako DS v signaturi