UP - logo
Narodna in univerzitetna knjižnica, Ljubljana (NUK)
Naročanje gradiva za izposojo na dom
Naročanje gradiva za izposojo v čitalnice
Naročanje kopij člankov
Urnik dostave gradiva z oznako DS v signaturi
  • The role of saliva in the prevention of intraoral complications following irradiation = Vloga sline pri preprečevanju intraoralnih zapletov po obsevanju
    Rode, Mirela
    Background. The aim of our study was to explain and estimate the effect of theparasympathomymetic pilocarpine and anticholinergic biperidene on the secretion and composition of saliva in patients ... with head and neck carcinoma and to evaluate their role in the prevention of irradiation side-effects in these patients. Our study is based on the hypothesis that in patients treated with irradiation for head and neck carcinoma, their glandular parenchyma can be successfuly protected against irradiation damages through inhibition of theparasympatheic system. After the irradiation treatment has been completed, the saliva production can be increased with stimulation of the parasympatheticsystem, which contributes to a decrease of the post-treatment xerostomia. Methods. 69 patients were randomly divided into three groups. A group patients received pilocarpine, B group patients received biperidene during their radiotherapy and pilocarpine afterwards, while C group patients received none of these medicaments as xerostomy prevention. The authors measured the quantities of saliva, the pH value and some salivary electrolytes. During the radiotherapy they also assesed the radiomucousitis degree. Results. Salivary secretion was the least affected in the group of patients who had been receiving biperidene. One year after radiotherapy had been finished, saliva could be measured only in these patients. During radiotherapy, a decrease of the pH value could be observed in all three groupsof patients. (Abstract truncated at 2000 characters.)
    Vir: Zdravniški vestnik : glasilo Slovenskega zdravniškega društva = Slovenian medical journal = journal of Slovenian Medical Association. - ISSN 1318-0347 (Letn. 69, št. 6, jun. 2000, str. 423-428)
    Vrsta gradiva - članek, sestavni del
    Leto - 2000
    Jezik - angleški
    COBISS.SI-ID - 11694041

Vnos na polico