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Epidemiologija invazivnih pnevmokoknih okužb v Sloveniji, 1997-1998 = Epidemiology of invasive infections with Streptococcus pneumoniae in Slovenia, 1997-1998Čižman, MilanBackground. Streptococcus pneumoniae is a common cause of morbidity in children and adults. Invasive infections with Streptococcus pneumoniae cause substantial mortality in adult patients. ... Epidemiology of invasive infections due to Streptococcus pneumoniae, the susceptibilities and serogroups/types demonstrate geographical variability and are not completely known. Patients and methods. From 1997 to 1998 all children and adults with Streptococcus pneumoniae isolated from blood, cerebrospinal fluid or other normally sterile body site were included in a prospective nationwide study. Results. During twoyears 254 invasive infections, 81 in children and 173 in adults (>15 years of age) were diagnosed. The overall annual incidence was 6.42 cases per 100,000 population; 46.73 for children =< 2 years and 13.9 for persons aged >= 65 years per 100,000population. Pneumonia, empyema, meningitis, bacteraemia/sepsis and other focal infections were found in adults in 74.6%, 10.4%, 7.4% and 7.6% and in children in 36.2%, 8.7%, 51.2% and 3.9% respectively. No deaths were recorder among children, adults case-fatality was20.8%. The 23-valent pneumococcal vaccine includes 93.7% of the invasive serotypes identified in adults in Slovenia. Pneumococcal groups/types 1,6,9,14,18,19 and 23, comprised 85.1% of all invasive pneumococcal infectionsin children. Overall resistance to penicillin, erythromycin, trimetoprim/sulfamethoxazole, tetracycline, chloramphenicot, cefotaxime and ceftriaxone was 14.6%, 4.0%, 19.4%, 5.5%, 2.9%, 3.8% and 3.4%. Conclusions. The study showed a lower incidence of invasive pneumococcal infections as compared to the studies published to date. To find out realistic data the causes of invasive infections should be searched more frequently. In Slovenia the treatment of pneumococcal infections should be improved. (Abstract truncated at 2000 characters.)Vir: Zdravniški vestnik : glasilo Slovenskega zdravniškega društva = Slovenian medical journal = journal of Slovenian Medical Association. - ISSN 1318-0347 (Letn. 69, št. 9, sep. 2000, str. 587-592)Vrsta gradiva - članek, sestavni delLeto - 2000Jezik - slovenskiCOBISS.SI-ID - 12153817
Avtor
Čižman, Milan
Teme
Pneumococcal infections |
Epidemiology |
Streptococcus pneumoniae |
Isolation and purification |
Incidence |
Bacteremia |
Sepsis |
Pneumonia, lobar |
Meningitis, pneumococcal |
Hospitalization |
Antibiotics |
Drug resistance, microbial |
Prospective studies |
bakterijske infekcije |
epidemiologija |
streptokoki |
Slovenija
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vir: Zdravniški vestnik : glasilo Slovenskega zdravniškega društva = Slovenian medical journal = journal of Slovenian Medical Association. - ISSN 1318-0347 (Letn. 69, št. 9, sep. 2000, str. 587-592)
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